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 (rĭ-sûr′pēn′, -pĭn, rĕs′ər-pĭn, -pēn′, rĕz′-)
A drug, C33H40N2O9, isolated from the roots of certain species of rauwolfia and used as an antihypertensive.

[German Reserpin, from shortening and alteration of New Latin Rauvolfia serpentīna, species of snakeroot : rauwolfia + Late Latin serpentīna, feminine of serpentīnus, serpentine; see serpentine.]


(Pharmacology) an insoluble alkaloid, extracted from the roots of the plant Rauwolfia serpentina, used medicinally to lower blood pressure and as a sedative and tranquillizer. Its main adverse effect is mental depression. Formula: C33H40N2O9
[C20: from German Reserpin, probably from the New Latin name of the plant]


(rəˈsɜr pɪn, -pin)

an alkaloid, C33H40N2O9, obtained from the root of the rauwolfia, Rauwolfia serpentina, used in the treatment of hypertension.
[1950–55; < German Reserpin=reserp- (probably irreg. < New Latin Rauwolfia serpentina (Rauwolfia rauwolfia + Late Latin serpentīna, feminine of serpentīnus serpentine1)) + German -in -ine2]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.reserpine - antihypertensive consisting of an alkaloid extracted from the plant Rauwolfia serpentina (trade names Raudixin or Rau-Sed or Sandril or Serpasil)
antihypertensive, antihypertensive drug - a drug that reduces high blood pressure
rauwolfia - any of several alkaloids extracted from the shrub Rauwolfia serpentina


n reserpina
References in periodicals archive ?
My last remuneration for a drug study was more than 45 years ago, when I tested a combination of dioxolane and reserpine.
Effect of reserpine on salivary gland radioiodine uptake in thyroid cancer.
Reserpine, an antihypertensive drug used during the 1950s, was associated with a 5-20% risk of depression because it depletes serotonin, norepinephrine, and perhaps dopamine or epinephrine.
Phenobarbital, Dilantin, and Reserpine (an antihypertensive medication) have been known to accelerate thyroid dysfunction in the elderly.
Antihypertensives (with central nervous system effects) -- Aldomet, Wytensin, Tenex, Catapres, Ismelin, Hylorel, reserpine, Inderal, Corgard, Tenormin, Blocadren, Lopressor, Visken, Normodyne/Trandate, Sectral, Levatol, Cartol, Isoptin/Calan/Verelan, Kerlone
reserpine, labetalol), antidepressants that inhibit norepinephrine transporter function (e.
Opiates, interferon, steroids, reserpine, and other drugs can be depressogenic; on the other hand, steroids, anticholinergic agents, and antidepressants can induce mania.
1% formic acid and 5 [micro]l 10 [micro]M reserpine in methanol as an internal standard solution.
In the Veterans Administration (VA) Cooperative Trial, African American men comprised 42% of participants, all of whom were randomized to a combination of hydrochlorothiazide, reserpine, and hydralazine, or to placebo.
4% used diuretics, 13% angiotensin-converting enzyme (ACE) inhibitors, 11% beta-blockers and 6% reserpine and methyldopa.
No reduction of FQ MICs was observed with reserpine (10 rag/L), which indicated that resistance to FQ was not caused by an active efflux pump system.