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restriction endonuclease

   Also found in: Medical, Acronyms, Encyclopedia, Wikipedia 0.01 sec.
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Noun1.restriction endonuclease - any of the enzymes that cut nucleic acid at specific restriction sites and produce restriction fragments; obtained from bacteria (where they cripple viral invaders); used in recombinant DNA technology
endonuclease - a nuclease that cleaves nucleic acids at interior bonds and so produces fragments of various sizes


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coli protein expression vector using polymerase chain reaction (PCR), restriction endonuclease digestion, and DNA ligation.
2008) greatly facilitated optimization of the key by allowing us to perform virtual restriction endonuclease digestion (VRED) analyses, which saved time by eliminating much of the laboratory-intense trial-and-error usually associated with identifying informative restriction endonucleases.
 
 
 
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