RFLP

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RFLP

abbreviation for
(Genetics) restriction fragment length polymorphism: any variation in DNA between individuals revealed by restriction enzymes that cut DNA into fragments of different lengths in consequence of such variations. It is used forensically and in the diagnosis of hereditary disease. Also called: riflip

RFLP

(ˈrɪfˌlɪp)
n.
restriction fragment length polymorphism: a fragment of DNA, cut by a restriction enzyme, that is different in length for each genetically related group and is used to trace family relationships. Also called riflip.
[1985–90]
References in periodicals archive ?
Two functional SNPs, +1082G/A (a silent mutation in exon 5) and +1730G/A (3' untranslated region of the exon 8),and one intron,rs1256030C/T, in the E5R2 gene were genotyped, using polymerase chain reaction- restriction fragment length polymorphism (PCR-RFLP) analysis.
1787G>A) in prothrombin gen by polymerase chain reaction with restriction fragment length polymorphism (PCR-RFLP) method.
Blood samples were taken and genotyping was performed by restriction fragment length polymorphism (RFLP) approach.
The polymerase chain reaction- restriction fragment length polymorphism (PCR-RFLP) or cleaved amplified polymorphic sequence (CAPS) is a less expensive method capable of locating genes associated with certain genetic disorders [14].
GSTP1 and GC polymorphisms were determined by using restriction fragment length polymorphism (RFLP) technique.
However, these two viruses can be distinguished if PCR is combined with a restriction fragment length polymorphism (RFLP) assay (Hosamani et al.
Because a large fraction of the intestinal community is difficult or not posible to culture, molecular approaches such as Restriction Fragment Length Polymorphism (RFLP), has been shown to be an useful tool for the study of diet-associated changes in gut microbial communities.
Molecular identification was conducted at Seoul National University Bundang Hospital, where PCR restriction fragment length polymorphism and multiplex real-time PCR and melting curve analyses were performed as described (5,6).
Variation in restriction fragment length polymorphism could be seen.
It has several known allelic variants including a FokI restriction fragment length polymorphism in exon II, BsmI and ApaI polymorphisms in the intron between exons VIII and IX, and a mononucleotide [[(A).
The DNA analysis method is based on PCR restriction fragment length polymorphism (PCR-RFLP).

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