retinitis pigmentosa


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retinitis pig·men·to·sa

 (pĭg′mĕn-tō′sə, -mən-)
n.
A hereditary degenerative disease of the retina, characterized by night blindness, pigmentary changes within the retina, and eventual loss of vision.

[New Latin pigmentōsa, feminine of pigmentōsus, pigmented.]

retinitis pigmentosa

(ˌpɪɡmənˈtəʊsə)
n
(Medicine) a degenerative hereditary disease of the human eye, characterized by pigmentary changes in the retina, night blindness, and eventual loss of vision
[C19: pigmentosa, feminine of Latin pigmentosus]

retini′tis pig•men•to′sa

(ˌpɪg mɛnˈtoʊ sə, -mən-)
n.
degeneration of the retina manifested by night blindness and gradual loss of peripheral vision, eventually resulting in tunnel vision or total blindness.
[1860–65; < New Latin: pigmentary retinitis. See pigment, -ose1]

retinitis pigmentosa

Degeneration of the light-sensitive cells of the retina.
References in periodicals archive ?
The UK Medicines and Healthcare Regulatory Agency (MHRA) has accepted Paris, France-based clinical-stage biopharma company GenSight Biologics' (Paris, Euronext: SIGHT) clinical trial application to initiate the PIONEER Phase I/II study of GS030 in patients with retinitis pigmentosa, the company said.
Epidemiological data of retinitis pigmentosa (RP) show that 1/3500 individuals are suffered with this devastating disease and most common incidences been reported from developing countries (Jay, 1982; Ayuso and Millan, 2010).
A comprehensive literature search was carried out using MEDLINE and CINAHL databases and all relevant articles on causative mutations for non-syndromic Retinitis pigmentosa from 1999 till 2015 were included.
Pipeline Products for Retinitis Pigmentosa (Retinitis) - Overview 9
The device, developed by medical products developer Second Sight, has been implanted in several UK patients with retinitis pigmentosa and age-related macular degeneration.
These visual impairment disorders include retinitis pigmentosa, keratoconus, cataract, nystagmus, astigmatism, glaucoma, microphthalmia, anophthalmia, strabismus and myopia.
The acquisition of RetroSense and its RST-001 program builds on Allergan's deep commitment to eye care, and our focus on investing in game-changing innovation for retinal conditions, including Retinitis Pigmentosa, where patients desperately need treatment options," said Brent Saunders, CEO and President of Allergan.
Retinitis Pigmentosa is a group of rare, inherited genetic disorders characterized by progressive peripheral vision loss and night vision difficulties followed by eventual central vision loss and blindness in many cases.
The report provides comprehensive information on the therapeutics under development for Retinitis Pigmentosa (Retinitis), complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type.
The prevalence of cystoid macular oedema on optical coherence tomography in retinitis pigmentosa patients without cystic changes on fundus examination.
The researchers created stem cells from a sample of skin that was taken from a patient with retinitis pigmentosa.
In the first, the self-reported sleep problems of individuals with retinitis pigmentosa were examined and, in the second, an attempt was made to determine if those who have a genetic mutation that causes their visual disorder but is also expressed in the pineal gland are more likely to experience sleep-related difficulties than those whose mutation is expressed only in the retina.