retinoic acid


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Related to retinoic acid: vitamin A

ret·i·no·ic acid

 (rĕt′n-ō′ĭk)
n.
1. A vitamin A derivative, C20H28O2, that serves as a regulator of morphogenesis and functions in the growth and development of bone and the maintenance of epithelium.
2. Either of two isomers of this compound, tretinoin or isotretinoin, that are used as drugs chiefly to treat acne. In both senses also called vitamin A acid.

Translations

retinoic acid

n ácido retinoico
References in periodicals archive ?
Patent and Trademark Office has issued two patents covering methods for stratifying patients with acute myeloid leukemi and myelodysplastic syndrome for treatment with SY-1425, the company's first-in-class selective retinoic acid receptor alpha agonist.
This means that their content is not known but common agents include hydroquinone, mercury, salicylic acid, retinoic acid and steroids.
Don't be dismayed to see a chemical peel as Retinoic acid Facial Peel is a wise choice for people who want a lifting effect.
3g of retinoic acid via yolk sac to induce a defective model of a thymus with hypoplasia.
Experimental work12 clearly elucidates the requirement of retinoic acid for the initiation of outgrowth in the chick limb bud.
And retinaldehyde dehydrogenases (RALDH) oxidize retinaldehyde to retinoic acid, primarily by RADLH1 [6].
VTP-43742 is a phase II orally active retinoic acid receptor-related orphan receptor gamma t inhibitor indicated for psoriasis and other autoimmune disorders.
Other topics include the transcriptional control of dendritic cell development, the genomics of immune diseases and new therapies, chemokines and chemokine receptors in lymphoid tissue dynamics, the innate lymphoid cell precursor, retinoic acid and retinoic acid receptors as pleiotropic modulators of the immune system, auto-antigens as partners in the initiation and propagation of autoimmune rheumatic diseases, fate mapping and quantitation of hematopoiesis in vivo, coinhibitory pathways in immunotherapy for cancer, and broadly neutralized antibodies to HIV and their role in vaccine design.
3] This translocation results in the fusion of the promyelocytic leukemia gene "PML" and the retinoic acid receptor (RAR[alpha]) gene.
4,5) Usually, APL is sensitive to the differentiating effect of all-iraws retinoic acid (ATRA) and arsenic trioxide (ATO).
To interact with retinoid receptors, retinol must first be metabolized to more active forms, such as retinaldehyde and retinoic acid using several enzymatic steps.

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