reverse transcriptase

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A polymerase that catalyzes the formation of DNA on an RNA template, found in oncogenic viruses containing RNA, especially the retroviruses.

reverse transcriptase [trænˈskrɪpteɪz]

(Life Sciences & Allied Applications / Biochemistry) an enzyme present in retroviruses that copies RNA into DNA, thus reversing the usual flow of genetic information in which DNA is copied into RNA

reverse transcriptase

Any of a class of enzymes that catalyze the formation of DNA from an RNA template and are found in retroviruses, and also in certain body cells (such as stem cells) as the enzyme telomerase. The action of reverse transcriptase runs in the opposite direction from normal genetic transcription in the cell, in which RNA is copied from DNA. Drugs that inhibit the action of viral reverse transcriptase have been used to treat retroviral infections such as AIDS, and those that inhibit telomerase are potential anticancer agents.

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Noun

reverse transcriptase - a polymerase that catalyzes the formation of DNA using RNA as a template; found especially in retroviruses

polymerase - an enzyme that catalyzes the formation of new DNA and RNA from an existing strand of DNA or RNA

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3TC antiviral antiviral agent antiviral drug AZT complementary DNA delavirdine drug cocktail HAART highly active antiretroviral therapy lamivudine nevirapine NNRTI non-nucleoside reverse transcriptase inhibitor NRTI nucleoside analogue nucleoside reverse transcriptase inhibitor polymerase Rescriptor			Under the agreement, Agilent will make a payment to Invitrogen for an undisclosed amount and discontinue sales of RNase H minus reverse transcriptase products. Invitrogen and Agilent settle patent suits by Instrument Business Outlook A single dose of tenofovir and emtricitabine at delivery reduced resistance to nonnucleoside reverse transcriptase inhibitors at 6 weeks after delivery by half. A single dose of tenofovir and emtricitabine can reduce resistance by Farham, Bridget / CME: Your SA Journal of CPD The drug stops HIV from reproducing by blocking the reverse transcriptase enzyme, which normally allows the virus to replicate and spread. Tests suggest new microbicide will have improved efficacy by Population Briefs			reverist revers reversal reversal film reverse Reverse arms Reverse bearing reverse commute Reverse curve reverse discrimination reverse dive reverse fault Reverse fire reverse gear reverse hang reverse lightning reverse mortgage Reverse operation reverse osmosis reverse out reverse Polish notation reverse slope reverse split reverse stock split reverse takeover reverse transcriptase reverse transcriptase inhibitor reverse transcription reverse video reverse-charge reverse-charge call reverse-engineer Reversed Reversed positive Reversedly Reverseless Reversely Reverser reversi reversibility reversible reversible cloth reversible jacket Reversible lock reversible process Reversibly reversing Reversing engine Reversing gear reversing light reversing lights			reverse swap Reverse Swaps Reverse T3 Reverse T3 Reverse Take-Over Reverse takeover Reverse takeover reverse takeovers reverse takeovers Reverse tarot meaning Reverse tarot meaning Reverse taxation reverse telecine Reverse telnet Reverse Tetracycline Transactivator Reverse Tetracycline-Regulated Retroviral Vector Reverse Tool Order reverse torque test reverse torque test reverse torque test reverse torque test reverse torque test Reverse Traffic Channel Reverse transcribed Reverse transcribed Reverse transcribed Reverse transcribing Reverse transcribing Reverse transcribing reverse transcript reverse transcriptase Reverse Transcriptase and Polymerase Chain Reaction Reverse Transcriptase In Situ Polymerase Chain Reaction reverse transcriptase inhibitor reverse transcriptase inhibitor reverse transcriptase inhibitor reverse transcriptase inhibitor reverse transcriptase inhibitor Reverse transcriptase inhibitors Reverse transcriptase inhibitors Reverse Transcriptase Nucleoside Inhibitor Reverse Transcriptase Polymerase Chain Reaction Reverse Transcriptase Positive Reverse Transcriptase Primer Extension Reverse Transcriptase Recognition Signal Reverse Transcriptase-Polymerase Chain Reaction Reverse Transcriptase-Polymerase Chain Reaction Method Reverse Transcriptase-Polymerase Chain Reaction Technique reverse transcription reverse transcription reverse transcription reverse transcription Reverse Transcription and Competitive Polymerase Chain Reaction Reverse Transcription and Nested Polymerase Chain Reaction Reverse Transcription and Polymerase Chain Reaction Analysis Reverse Transcription Intron Differential Polymerase Chain Reaction Reverse Transcription with the Random Oligonucleotide Libraries Reverse transcription-polymerase chain reaction reverse transcriptions reverse transcriptions Reverse Transfer Arc

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