London, Jan 7 (ANI): A powerful new class of tools, developed by neuroscientists at the Massachusetts Institute of Technology, could reversibly
shut down brain activity by using different colours of light.
Aptamer sensors, according to the researchers, are also capable of being reversibly
denatured, meaning they can easily release their target molecules, which makes them perfect receptors for biosensing applications.
The incorporation of "on/off switches" into next generation CAR products will provide physicians with the potential to rapidly control and reversibly
titrate the activity of CAR T-cells.
Senis revealed that a drug that reversibly
blocked CD148 would be safer because it would only affect one pathway, dampening clotting but leaving some control over bleeding.
The three types of confined spaces we propose are as follows: 1) nanopores within reversibly
self-assembling colloidal crystals (""dynamic nanoflasks""), 2) cavities of bowl-shaped metallic nanoparticles (NPs), and 3) surfaces of spherical NPs.
Electrochromics is the process of reversibly
darkening specially prepared transparent materials through controlled application of an electric current.
Thus, in analogy to the polymerase chain reaction (PCR) for DNA replication, single tri-valent colloids will reversibly
attach to the colloidal master strand, followed by inter-particle crosslinking of the newly formed strand, which then is detached form the master by opening the bonds between the strands.
Electrochromics is the science of reversibly
darkening materials using electricity.
Individual molecules can be reversibly
activated by various means such as light, chemicals and external electrical or magnetic fields.
Like other molecules of this class, the compound reversibly
inhibits immunocompetent lymphocytes, particularly T-lymphocytes, and it also inhibits lymphokine production and release.
We will apply three strategies to control the spatial arrangement of the magnetic moments in EMF-SMMs: (i) deposition of EMF molecules via sublimation; (ii) exohedral modification of EMFs with anchoring groups for grafting of EMFs on surfaces; (iii) introducing photoswitchable units into the anchoring groups which can reversibly
change their geometry upon impact of light and will allow switching direction of the magnetic moment in a fully controllable way.
Neurons expressing channelrhodopsin-2 (ChR2) can be depolarized rapidly and reversibly
by illumination, hence allowing control of the activation/inactivation of neurons in specific locations of the brain.