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One of the repeating contractile segments into which a myofibril is divided, composed of actin and myosin filaments and giving striated muscle its distinctive bands.


(Anatomy) any of the units that together comprise skeletal muscle


(ˈsɑr kəˌmɪər)

any of the segments of myofibril in striated muscle fibers.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.sarcomere - one of the segments into which a myofibril is divided
myofibril, myofibrilla, sarcostyle - one of many contractile filaments that make up a striated muscle fiber
segment - one of the parts into which something naturally divides; "a segment of an orange"
References in periodicals archive ?
2004) commented that shear force value and sarcomere length determined instrumentally could be applied to predict the descriptive sensory hardness of broiler breast meat.
It turns out that C protein sensitizes certain parts of the sarcomere to calcium.
We previously established that, using skinned muscle fibers placed in a Ca buffer, each sarcomere exhibited stable auto-oscillation of contraction and elongation under the fixed Ca concentration of approximately 1 uM, through careful measurements of muscle fiber tension (especially using thin bundles of myofibrils ~1 um in diameter); we termed this phenomenon as spontaneous oscillatory contraction (SPOC) (see recent review by S.
The literature describes several viscoelastic properties of skeletal muscle (stress relaxation, creep, and hysteresis) that may explain increased sarcomere compliance and the lengthening process, but there is still some debate as to how much of the change is mechanical/structural and how much is functional/neurological (3), (4).
Activation of cMLCK and MLC-2v are known to increase sarcomere reorganization and cardiac contractility and prevent cardiac decompensation from heart failure.
Effect of postrigor sarcomere length on mechanical and structural characteristics of raw and heat-denatured single pork muscle fibres.
Williams PE (1990) Use of intermittent stretch in the prevention of serial sarcomere loss in immobilised muscle.
Combined with the use of a single ATP, the interaction of myosin and actin creates movement and shortens the sarcomere.
Isotonic, also described as aerobic, exercise types are exercises that result in sarcomere length changes in big muscle groups without changes in muscle tension.
Hypertrophic cardiomyopathy (HCM), an autosomal dominant inherited syndrome, is a disease of the sarcomere and is the most common cause of SCD in individuals less than 35 years of age.
The sarcomere, or the unit of contraction, contains molecules that modulate contractions and regulate assembly and disassembly in training or disuse.
For example, sequence variants in the PCSK9 gene were associated with lower LDL cholesterol and protection from CVD, single gene mutations in sarcomere genes were associated with a small but significant proportion of men and women with left ventricular hypertrophy (LVH) (76,77).