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Related to schistocyte: target cell, microspherocyte, burr cell


A red blood cell having an abnormal shape as a result of fragmentation that occurs as the cell flows through damaged small vessels.

[Greek skhistos, split; see schist + -cyte.]
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Peripheral blood smears were routinely prepared from all TTP patients and frequency of the schistocyte on the blood film was estimated as mild, moderate and severe at 1000X magnification.
9]), increased lactate dehydrogenase activity (517 IU/L) and schistocyte count was 3%.
Evidence for microangiopathic haemolysis should be sought by monitoring platelet count, haemoglobin, lactate dehydrogenase and schistocyte measurements on the peripheral smear.
Red cell morpho- logy was normochromic normocytic with microsphe- rocytes and an occasional schistocyte.
An occasional ([less than]1%) schistocyte or helmet cell also may be seen.
Serum markers of TA-TMA include elevated lactate dehydrogenase, de novo thrombocytopenia not explained by other post-HSCT complications, Coombs test-negative hemolytic anemia (often hallmarked by increased free plasma hemoglobin and decreased haptoglobin), peripheral schistocytes, and signs of renal dysfunction (proteinuria and elevated creatinine).
Hematological markers demonstrated HCT-TMA with thrombocytopenia, elevated lactate dehydrogenase, and schistocytes.
Neutrophil Changes Erythrocyte Changes Cytoplasmic vacuoles Crenated (burr cells, echinocytes) Loss of granulations Spherocytes Elongated nuclei Elongated (elliptocytes) (loss of segmentation) Undefined chromatin Schistocytes (fragments) (appear liquefied) Pyknotic nuclei (necrobiotic) Hypochromic Cytoplasm rupture Smudge (basket) cells
1g/dl) and thrombocytopenia (plt=84*10^9/L) with 7% schistocytes on peripheral smear.
Peripheral blood films in these cases revealed hypochromia and microcytosis, target cells and schistocytes and pencil cells in those with iron deficiency complicating beta thalassemia trait.
9, blood picture showed schistocytes = 2 + RBG = 18 mmol/L, reticulocytes = 1.