scopolamine


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sco·pol·a·mine

 (skə-pŏl′ə-mēn′, -mĭn)
n.
An alkaloid drug, C17H21NO4, extracted from plants such as henbane and used primarily to treat motion sickness and nausea and to dilate the pupil. Also called hyoscine.

[New Latin Scopolia, plant genus (after Giovanni Antonio Scopoli (1723-1788), Italian naturalist) + -amine.]

scopolamine

(skəˈpɒləˌmiːn; -mɪn; ˌskəʊpəˈlæmɪn)
n
(Biochemistry) a colourless viscous liquid alkaloid extracted from certain plants, such as henbane: used in preventing travel sickness and as an anticholinergic, sedative, and truth serum. Formula: C17H21NO4. Also called: hyoscine See also atropine
[C20 scopol- from New Latin scopolia Japonica Japanese belladonna (from which the alkaloid is extracted), named after G. A. Scopoli (1723–88), Italian naturalist, + amine]

sco•pol•a•mine

(skəˈpɒl əˌmin, -mɪn, ˌskoʊ pəˈlæm ɪn)

n.
a colorless, syrupy, water-soluble alkaloid, C17H21NO4, obtained from certain plants of the nightshade family, used as a sedative, antinauseant, and to dilate the pupils.
[1890–95; < New Latin Scopol(ia japonica) Japanese belladonna (genus Scopolia after German. A. Scopoli (1723–88), Italian naturalist]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.scopolamine - an alkaloid with anticholinergic effects that is used as a sedative and to treat nausea and to dilate the pupils in ophthalmic procedures; "transdermal scopolamine is used to treat motion sickness"; "someone sedated with scopolamine has difficulty lying"
alkaloid - natural bases containing nitrogen found in plants
Translations
scopolamine

scopolamine

n escopolamina, hyoscina (INN)
References in periodicals archive ?
2] Bacopa monniera(CDRI-08) Upregulates the Expression of Neuronal and Glial Plasticity Markers in the Brain of Scopolamine Induced Amnesic Mice, Arpita Konar, Akash Gautam, and M.
Contract awarded for Purchase Scopolamine Butylbromide (Hyoscine), Vo, Provision For The Department Of Health Services (Pharmacy) Health Region Of Saints
Datura plant is one of the most important medical plants in the world for its medical importance, either in the traditional or constitutional medicine as a main resource of Tropanealkaloids; in particular hyoscyamine, scopolamine and atropine.
The cholinergic agent physostigmine is capable of reversing the central nervous system effects of anticholinergics, such as scopolamine and tricyclic antidepressants.
3]-receptor antagonist improves memory retention and reverses the cognitive deficit induced by scopolamine in a two-trial place recognition task; while post-training systemic administration of thioperamide (THIO) facilitated memory consolidation in mice (6).
The patients were treated with a scopolamine transdermal release system applied to hairless skin overlying the parotid region.
Scopolamine hydrobromide, scopolamine methyl bromide and oxotremorine hydrochloride (Sigma Chemical Co.
In addition to intranasal apomorphine for treatment of sexual dysfunction, Nastech has several products in clinical development including intranasal scopolamine for the prevention and treatment of motion sickness, intranasal morphine for the treatment of moderate to severe pain, including breakthrough pain, and intranasal butorphanol for the treatment of acute migraine pain.
Nguyen, Noven Process Development Engineer, presented the results of a study entitled "In-Vitro to In-Vivo Evaluation for Scopolamine Transdermal Delivery.
In addition to intranasal morphine for treatment of moderate-to-severe pain, including breakthrough pain, Nastech has several products in clinical development including intranasal scopolamine hydrobromide for the prevention and treatment of motion sickness, intranasal apomorphine for the treatment of sexual dysfunction, and intranasal butorphanol for the treatment of acute migraine pain.
The Company has additional investigational product candidates in various stages of development: OTS(TM) nicotine for smoking cessation, OTS fentanyl for acute pain management, OTS etomidate for short-acting sedation, OTS piroxicam for mild to moderate pain, OTS droperidol and OTS prochlorperazine for nausea and vomiting, and OTS scopolamine for motion sickness.
announced today that Nastech Pharmaceutical Company reacquired the US marketing rights to intranasal scopolamine for motion sickness.