New successful uses include the treatment of common tropical diseases such as Dengue Fever (50 to 100 million infections worldwide annually) and Scrub Typhus
(1 million infections worldwide annually)
Three weeks ago, she was diagnosed as scrub typhus
with fever, severe myalgia, arthralgia, rash, and eschar in the right arm at another hospital (Figure 1).
To the Editor: Infections with typhus group rickettsiae (TGR), spotted fever group rickettsiae (SFGR), and scrub typhus
group orientiae (STGO) have been reported among persons in South Korea in increasing numbers over the past decade (1,2).
tions of scrub typhus
which manifests as a nonproductive cough and breathlessness and leads to ARDS which could be life- threatening.
is a common infectious disease in tropical countries but has protean manifestations.
, a disease commonly found in regions having dense vegetation, is spreading fast in the urban areas of Punjab, Haryana, Chandigarh and Himachal Pradesh.
These diseases--including scrub typhus
and spotted fever--take their name from the bacterial genus Rickettsia, one of the implicated pathogens.
military asked USDA to support the war effort by developing products to protect personnel from insect-transmitted diseases, especially plague, malaria, scrub typhus
, epidemic typhus, and dengue.
Individual chapters then take up diseases typical of such areas, particularly tropical ones: leptospirosis, malaria, leishmaniasis, dengue virus infection, chikungunya fever, Japanese encephalitis, gastrointestinal infectious disease, hepatitis, tuberculosis, bird flu, scrub typhus
, and HIV and related emerging infections.
Later, this method was adopted for use against malaria and other diseases caused by vector-borne pathogens, but it was the effects of scrub typhus
that eventually led to the development of permethrin uniform treatments used by US military forces and similarly treated clothing made available to nonmilitary consumers.
Rickettsia infections, particularly epidemic or louse-borne typhus, which emerges in situations of human upheaval such as war; the milder endemic or murine typhus in Europe and North Africa; and scrub typhus
(Tutsugamushi fever) in the Far East, were major problems, affecting war-torn communities and combatants.
tritaeniorhynchus), scrub typhus
transmitted to humans via mites on rodents to bovine tropical theileriosis in cattle.