The bodies of serotonergic
neurons are located in the CNS structures called the raphe nuclei.
Ingrezza selectively inhibits VMAT2 with no appreciable binding affinity for VMAT1, dopaminergic (including D2), serotonergic
, adrenergic, histaminergic, or muscarinic receptors.
SAN FRANCISCO--Hoarding disorder is characterized by a distinct pattern of serotonergic
dysfunction different from that seen in obsessive-compulsive disorder or major depression, Sanjaya Saxena, MD, reported at the annual conference of the Anxiety and Depression Association of America.
It is also an intermediate of the phosphatidylinositol cycle, a second-messenger neuronal signaling system used by noradrenergic, serotonergic
, and cholinergic receptors.
Dysregulation of the serotonergic
system is thought to have an important role in the pathophysiology of the disorder.
Brahmi knonw as Bacopa monnieri, is one of the popular natural brain supplements in Brahmpushpi capsules, helps in enhancing the flow of dopamine and other serotonergic
As a selective serotonin inverse agonist (SSIA), pimavanserin is a new class of antipsychotic medication with a distinct mechanism of action targeting serotonergic
5-HT2A receptors while avoiding activity at dopamine and other receptors commonly targeted by other antipsychotics.
The authors reported that there might be a relationship between OB syndrome, which presents as serotonergic
dysfunction, and anxious temperament.
sup] Serotonin syndrome (SS) is a potentially life-threatening adverse drug reaction to serotonergic
Conclusion: Inability of paroxetine to enhance the serotonergic
transmission in vitro causes a decrease in its qualitative response.
Initiate cyproheptadine at 4 mg/d, titrate every 2 or 3 days, and monitor for sedation, confusion, or reduced efficacy of concurrent serotonergic
Serotonin syndrome is a potentially life-threatening drug reaction caused by excessive serotonergic
activity in the nervous system.