sickle cell

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sickle cell

n.
An abnormal, crescent-shaped red blood cell that results from a single change in the amino acid sequence of the cell's hemoglobin, which causes the cell to contort, especially under low-oxygen conditions.

sick′le cell`



n.
an elongated, often sickle-shaped red blood cell, caused by defective hemoglobin.
[1925–30]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.sickle cell - an abnormal red blood cell that has a crescent shape and an abnormal form of hemoglobin
erythrocyte, RBC, red blood cell - a mature blood cell that contains hemoglobin to carry oxygen to the bodily tissues; a biconcave disc that has no nucleus
References in periodicals archive ?
The test can spot congenital hypothyroidism, cystic fibrosis, inherited metabolic disorders and sickle cell disorders.
Sickle cell disorders (SCDs) that are characterized by the presence of hemoglobin S (HbS) in red cells [1] refer to a group of disorders caused by autosomal recessive inheritance of a pair of abnormal hemoglobin genes, including the sickle cell gene.
11% of children with sickle cell disorders received 1st blood transfusion at the age of 0-2 yrs.
Early detection of babies at risk of sickle cell disorders and early commencement of treatment has been shown to be beneficial in affected infants.
Although sickle cell disorders are not common in Colombia, their frequency is higher along the Caribbean coast (including Atlantico Department) and 2 times that of the rest of Colombia) (6).
Chromatographic analysis of Hb S for the diagnosis of various sickle cell disorders in Pakistan.
As well as being crucial for emergency situations and during surgery, donor blood is needed for patients with cancer and for the regular transfusions that treat and keep alive people with certain blood conditions, including sickle cell disorders and thalassemia.
Indeed, some rarer types are only found within the black and South Asian communities, which happen to have a high prevalence of Sickle Cell Disorders and Thalassemia - conditions requiring regular blood transfusions - so it's absolutely vital that people in these communities come forward to donate.
Sickle cell disorders are seen commonly in Sub-Saharan Africa but also occur in Mediterranean, India and Arabian Pninsula.
Sickle cell disorders are a group of autosomal recessive disorders, caused by point mutation at the sixth position in beta globin chain, valine substituting glutamic acid.
The Dubai Islamic Humanitarian Foundation, a non-profit charitable foundation and a subsidiary of Dubai Islamic Bank (DIB), sponsored a state-of-the-art machine for the Thalassemia centre to help patients with sickle cell disorders.
Data derived from this study will contribute in optimizing our standard of care as well as initiate a program for the prevention of sickle cell disorders in our locality.

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