sickle cell

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sickle cell

n.
An abnormal, crescent-shaped red blood cell that results from a single change in the amino acid sequence of the cell's hemoglobin, which causes the cell to contort, especially under low-oxygen conditions.

sick′le cell`



n.
an elongated, often sickle-shaped red blood cell, caused by defective hemoglobin.
[1925–30]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.sickle cell - an abnormal red blood cell that has a crescent shape and an abnormal form of hemoglobin
erythrocyte, RBC, red blood cell - a mature blood cell that contains hemoglobin to carry oxygen to the bodily tissues; a biconcave disc that has no nucleus
References in periodicals archive ?
As well as being crucial for emergency situations and during surgery, donor blood is needed for patients with cancer and for the regular transfusions that treat and keep alive people with certain blood conditions, including sickle cell disorders and thalassemia.
Indeed, some rarer types are only found within the black and South Asian communities, which happen to have a high prevalence of Sickle Cell Disorders and Thalassemia - conditions requiring regular blood transfusions - so it's absolutely vital that people in these communities come forward to donate.
Conditions currently screened for in Wales are congenital hypothyroidism, cystic fibrosis, medium chain acyl-CoA dehydrogenase deficiency (MCADD), phenylketonuria and sickle cell disorders.
Sickle cell disorders are a group of autosomal recessive disorders, caused by point mutation at the sixth position in beta globin chain, valine substituting glutamic acid.
The Dubai Islamic Humanitarian Foundation, a non-profit charitable foundation and a subsidiary of Dubai Islamic Bank (DIB), sponsored a state-of-the-art machine for the Thalassemia centre to help patients with sickle cell disorders.
Their topics include in vivo models for evaluating antithrombotics and thrombolytics, principle and practice in novel anticoagulant therapy, antithrombotic effects of naturally derived products on coagulation and platelet function, potential therapeutic and diagnostic implications of adhesion molecules, and the diagnosis and management of sickle cell disorders.
The conference will explore the health, justice and human rights issues raised by Sickle Cell disorders and deaths in custody.
The present study was undertaken to determine the prevalence of iron deficiency anaemia and the response of iron supplementation in sickle cell disorders in tribal population of the four States viz.
If only one of these genes is affected, the person has sickle cell trait which means that they don't have the symptoms of the sickle cell disorders, but they do have to be careful when doing things where there is less oxygen than normal - such as scuba diving, activities at high altitude and under general anaesthetics," he says.
As a result of this targeted partnership, MCADD was added to Georgia's series of Newborn Screenings because Georgia law (OCGA 31-12-6 & 31-12-7) and Rules and Regulations (Chapter 290-5-24) now require that every live born infant have an adequate blood test for nine treatable metabolic disorders (Phenylketonuria, Congenital Hypothyroidism, Maple Syrup Urine Disease, Galactosemia, Tyrosinemia, Homocystinuria, Congenital Adrenal Hyperplasia, Biotinidase Deficiency, Medium-Chain Acyl-CoA Dehydrogenase Deficiency) and for Sickle Cell disorders.
Careful microscopic examination of the placenta for this phenomenon may help detect patients with unsuspected sickle cell disorders or those with false-negative sickle tests.
To find prevalence of Sickle Cell Disorders in Residential Tribal School students

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