sickle cell trait


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sickle cell trait

n.
A hereditary condition, usually harmless and without symptoms, in which an individual carries only one mutated hemoglobin gene for sickle cell anemia. The sickle cell trait confers resistance to some forms of fatal malaria.

sick′le cell` trait`



n.
the usu. asymptomatic hereditary condition that occurs when a person inherits from only one parent the abnormal hemoglobin gene characteristic of sickle cell anemia.
[1925–30]
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References in periodicals archive ?
Unlike patients with SCD, who have two genes that cause the production of abnormal hemoglobin, individuals with sickle cell trait carry only one defective gene and typically live normal lives without health problems related to sickle cell.
One in 13 African Americans are carriers of the Sickle Cell trait, and a child whose parents are both carriers has a 25 percent chance of being diagnosed with Sickle Cell.
People who inherit two HbS genes develop sickle cell anaemia (HbSS) and those with one normal and one HbS gene become sickle cell trait (HbAS).
For the last two decades, they've had the option of artificially fertilising embryos and selecting only those that lack the sickle cell trait.
Individuals who inherit one copy of the altered gene and one normal gene are referred to as carriers of the disease and will have the genotype AS (heterozygous); these individuals will have sickle cell trait and are either asymptomatic or have only mild symptoms of the disease.
A 17-year-old boy with mild intermittent asthma and sickle cell trait presented with a 1-day history of persistent pain in his anterior lower legs.
The reported patients were associated with sickle cell hemoglobinopathy, mainly with sickle cell trait and less frequently without sickle cell disease.
African Americans who have sickle cell trait show lower hemoglobin [A.
Sickle cell disease affects about 1 in every 365 black births, with 1 in 13 black babies born with sickle cell trait.
A 30-year-old man with sickle cell trait presented to the emergency department with a sore throat, voice changes, and hemoptysis of 2 days' duration and acute onset of sharp pain in the neck that occurred after severe bouts of sneezing and coughing.
Of total 155 patients, 138 patients were of homozygous sickle cell anemia (SS) and 17 patients were of sickle cell trait (AS), who fulfilled inclusion and exclusion criteria as mentioned further.
However, the study found that carriers of the sickle cell trait were more likely to develop exertional rhabdomyolysis, a condition where skeletal muscle tissue breaks down, usually due to strenuous exercise.