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1. An infallible means of attack or defense.
2. A simple remedy for a difficult or intractable problem.
[From the belief that werewolves could be killed with silver bullets.]
informal a simple and immediate remedy for an intractable problem
[C20: from the belief in folklore that a werewolf can be killed only by a bullet made of silver]
a quick solution to a difficult problem.
[1930–35; from the belief that supernatural beings, as werewolves, can be killed with a silver bullet]