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Related to somatostatin: Octreotide


 (sō-măt′ə-stăt′n, sō′mə-tə-)
A polypeptide hormone produced chiefly by the hypothalamus that inhibits the secretion of various other hormones, such as somatotropin, glucagon, insulin, thyrotropin, and gastrin.


(Biochemistry) a peptide hormone that prevents the release of growth hormone from the pituitary gland
[C20: from somato- + -stat + -in]


(səˌmæt əˈstæt n)

a polypeptide hormone, produced in the brain and pancreas, that inhibits secretion of somatotropin from the hypothalamus and inhibits insulin production by the pancreas.
[1973; somato (tropin) + -stat + -in1]
References in periodicals archive ?
Non-parametric tests like Kruskal Wallis and Mann Whitney U-test were performed to show differences in SSTR receptor concentrations on parasite samples obtained from somatostatin untreated and treated groups of mice.
sup][6],[7],[8],[9],[10] TSHomas are often invasive and fibrous which hamper complete removal; somatostatin (SST) analogs are therefore primarily used in palliative care or for patients who were not cured by surgery.
5 months after surgery a PET-CT scan detected pathological mass (23 x 14 mm in size) with expression of somatostatin receptors (SSTR) in pancreas and metastases to regional lymph nodes.
Investigations include CT and MRI, and newer modalities, like endosonography and somatostatin receptor scintigraphy which are highly sensitive for detecting carcinoids presenting 80-100% sensitivity (8).
68Ga-DOTA-Tyr3-octreotide PET in neuroendocrine tumors: comparison with somatostatin receptor scintigraphy and CT.
A single dose of the somatostatin analog lanreotide cut the incidence of pain relapse after an episode of acute, necrotizing pancreatitis in a randomized, controlled study with 77 patients.
Other imaging modalities are less useful, such as angiography, transabdommal ultrasound, or somatostatin receptor scintigraphy.
Immunohistochemistry showed the nodules to be strongly positive for chromogranin (Figure 2), with focal positivity for insulin and somatostatin (Figure 3) following a physiologic staining pattern.
Meta-iodobenzyl guanidine [123]I and somatostatin scans were both negative.
9:30 "Localization of somatostatin mRNA in the brain and pancreas of rainbow trout (Oncorhynchus mykiss).

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