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sparteine

   Also found in: Medical, Encyclopedia, Wikipedia 0.03 sec.
spar·te·ine  (spärt-n, -n)
n.
A bitter, poisonous, liquid alkaloid, C15H26N2, obtained from the broom Cytisus scoparius or the lupin Lupinus luteus, whose sulfate has been used in medicine as a heart stimulant and as a way of inducing contraction of the uterus during labor.

[New Latin Spartium, broom genus (from Latin spartum, a kind of broom, from Greek sparton) + -ine.]

sparteine [ˈspɑːtɪˌiːn -ɪn]
n
(Chemistry / Elements & Compounds) a viscous oily alkaloid extracted from the broom plant and lupin seeds. It has been used in medicine to treat heart arrhythmias
[from New Latin Spartium, from Greek spartos broom]


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Commonly used prototype substrate reactions to characterize cytochrome P450 2D6 activity include bufuralol 1'-hydroxylation, debrisoquin 4-hydroxylation, sparteine oxidation, and dextromethorphan O-demethylation.
At about the same time, an inborn defect of the metabolism of a drug called debrisoquine was found in England[10] and of the drug sparteine in Germany.
 
 
 
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