spectinomycin


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spec·ti·no·my·cin

 (spĕk′tə-nō-mī′sĭn)
n.
A broad-spectrum antibiotic, C14H24N2O7, obtained from a species of gram-negative bacteria (Streptomyces spectabilis) or produced synthetically and used in its hydrochloride form especially in the treatment of penicillin-resistant gonorrhea.

[New Latin spect(ābilis), specific epithet (from Latin, visible, from spectāre, to watch; see spectacle) + (act)inomycin.]

spectinomycin

(ˌspɛktɪnəˈmaɪsɪn)
n
(Pharmacology) an antibiotic drug
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.spectinomycin - an antibiotic used to treat gonorrhea
antibiotic, antibiotic drug - a chemical substance derivable from a mold or bacterium that can kill microorganisms and cure bacterial infections; "when antibiotics were first discovered they were called wonder drugs"
Translations

spectinomycin

n espectinomicina
References in periodicals archive ?
The antimicrobial susceptibility testing panel should, at a minimum, include a fluoroquinolone, cefixime, ceftriaxone, spectinomycin, azithromycin, and any other drugs in local use for gonorrhea treatment.
However, it demonstrated susceptibility to spectinomycin (16 [micro]/mL) and reduced susceptibility to azithromycin (0.
For patients who may have acquired infection in certain parts of Asia, clinicians should consider treatment with cefixime, ceftriaxone, or spectinomycin when treatment with a cephalosporin is contraindicated.
Interpretive criteria based on expected treatment failure rates for single-agent therapy with penicillin, tetracycline, spectinomycin, or ceftriaxone have been selected (Table 1).
Susceptibility tests were performed for tetracycline (D and M), erythromycin (D and M), streptomycin (D and M), kanamycin (D), norfloxacin (D), pencillin (D), clindamycin (D), fusidic acid (D), rifampicin (D), cefoxitin (D), ceftiofur (M), chloramphenicol (M), ciprofloxacin (M), florfenicol (M), spectinomycin (M), sulfamethoxazole (M), tiamulin (M), and trimethoprim (M).
section]) Antimicrobial drugs (breakpoint final concentrations): S, streptomycin (16 mg/L); Su, sulfonamide (64 mg/L); T, tetracycline (8 mg/L); Cf, cefuroxime (16 mg/L); C, chloramphenicol (8 mg/L); Sp, spectinomycin (64 mg/L); Tm, trimethoprim (2 mg/L); A, ampicillin (8 mg/L]; G, gentamicin (4 mg/L); Ne, neomycin (8 mg/L) K, kanamycin (8 mg/L); Ak, amikacin (4 mg/L); Cx, cefalexin (16 mg/L); Cr, cefradine (16 mg/L); Cn, ceftriaxone (1 mg/L); Ct, cefotaxime (I m,-/L); Fu, furazolidone (8 mg/L); Nx, nalidixic acid (16 m,-/L).
For these 8 isolates, MICs of penicillin G, tetracycline, cefixime, cefdinir, cefodizime, ceftriaxone, levofloxacin, azithromycin, and spectinomycin were determined on chocolate agar (GC) medium base supplemented with 1% IsoVital X (Becton Dickinson, Franklin Lakes, N J, USA) and containing serial 2-fold dilutions of each agent (2).
Traditionally, most HA-MRSA isolates in the United States carry SCCmec type II (and to a lesser extent, SCCmec type III) that encodes resistance to [beta]-lactam antimicrobial agents bleomycin, macrolide-lincosamide-streptogamin B, aminoglycosides, and spectinomycin (38).
2] before being spread on blood agar plates containing 500 [micro]g/mL spectinomycin (17).
Specimens from all 70 patients had the same unique pattern of lysis when phage typed, had the same profile when examined by pulsed-field gel electrophoresis, and were resistant to ampicillin, streptomycin, spectinomycin, sulfonamides, tetracyclines, and trimethoprim.
One type, which is resistant to streptomycin, spectinomycin, trimethoprim, and sulfonamides, carries a chromosomally located class 2 integron with the dfrA1-sat1-aadA1 (Tn7) array of gene cassettes (2).