In this study, we aimed to determine the prevalence of MDR TB among new sputum
smearpositive patients for whom first-line treatment failed and to evaluate factors associated with an increased risk for MDR TB among these patients.
Pursuant to the license, INOH obtained exclusive rights to market the sputum
cytology and related technologies world- wide from Dr.
Bruce Rubin, MD, chair of pediatrics at the Virginia Commonwealth University Medical Center and a lead author of the study, said, "This study is consistent with smaller studies that have shown that guaifenesin has no measurable effect on sputum
properties or mucus clearance when taken by otherwise healthy adults who get a common cold.
The study took place between 1 August 2010 and 30 July 2012 and enrolled 384 children who had one paired induced sputum
and nasopharyngeal specimens-309 of the children had two paired specimens.
A major goal of APOPO's current research is to identify techniques for improving the rats' performance and increasing their operational efficiency, so that sputum
samples can be evaluated more quickly and accurately.
He said the symptoms of active TB of the lung are coughing, sometimes with sputum
or blood, chest pains, weakness, weight loss, fever and night sweats.
5 full-time staff to ensure continuous POC Xpert service: 1 person at the outdoor sputum
booth for patient assistance, sample buffering and data entry in the suspect register; 1 in the Xpert instrument room to perform the assay, communicate results to patients and healthcare workers and capture data in clinic file and TB registers; and a third person at 50% effort for assistance during the busy afternoon period and to cover for lunch breaks and absences.
Microscopic analysis of sputum
for TB is cheap and widely available, but misses half of all TB cases," said David Dowdy, MD PhD, assistant professor in the Department of Epidemiology at the Bloomberg School of Public Health and lead author of the study.
The animals were eventually able to test a dozen sputum
samples in about a minute, Poling told Science News.
peak expiratory flow rate (PEFR), hemogram, absolute eosinophil count (AEC), liver function test (LFT), kidney function test (KFT), blood sugar fasting and post prandial (F & pp), electro cardiogram (ECG), x-ray chest postero anterior (PA) view, sputum
culture (routine and fungus), urine and stool examination.
Patients with greater sputum
production may have more to gain, so further trials with participants with more severe disease should be conducted.
On the other hand, sputum
contains respiratory tract, oropharyngeal and nasopharyngeal secretions, as well as bacteria and products of inflammation, including DNA.