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An unsaturated aliphatic hydrocarbon, C30H50, that is the biosynthetic acyclic precursor to tetracyclic steroids such as cholesterol. It is widely found in animals, plants, and fungi and is present in high concentrations in shark liver oil and human sebum.

[New Latin Squalus, shark genus (from its occurrence in the liver oil of sharks) (from Latin squalus, a sea fish) + -ene.]


(Biochemistry) biochem a terpene first found in the liver of sharks but also present in the livers of most higher animals: an important precursor of cholesterol
[C20: from New Latin squalus genus name of the shark]


(ˈskweɪ lin)

an oil, C30H50, intermediate in the synthesis of cholesterol, obtained for use in manufacturing pharmaceuticals.
[1925–30; < New Latin Squal(us) a genus of sharks (the liver of which yields the oil), Latin: a kind of fish + -ene]
References in periodicals archive ?
Besides, sharks are also not the only source of squalene, a natural antioxidant; it may be extracted from some plants, too (like olives and palm oil) or produced artificially in a lab.
Out of 17, which are known as antitumor and anticancer agents through existing methods, piperidin-4-carboxylic acid and squalene, were taken (Fig.
The alpha-tocopherol rinseoff product also significantly inhibited photo-oxidation of squalene.
Squalene Market by Type (Animal-Sourced & Vegetable-Sourced) and End-Use Industry (Cosmetics, Pharmaceuticals & Food) - Global Forecasts to 2021
Y Squalene content and antioxidant activity of Terminalia catappaleaves and seeds.
They observe that while all olive oil provides a high amount of monounsaturated fatty acids (mainly oleic acid) as well as squalene, extra virgin olive oil also provides biologically active compounds that include the polyphenols oleocanthal, oleuropein, hydroxytyrosol, and lignans.
In the last decade, endogenously produced systemic and cutaneous redox-active substances (superoxide, hydrogen peroxide, NO, lipid peroxides, stable end products of lipid peroxidation, oxidative metabolites of cholesterol and squalene, etc.
In Fluad, the adjuvant is an oil-in-water emulsion of squalene oil, a naturally occurring substance in humans, animals and plants that is highly purified for making vaccines.
Fluad, which is manufactured using an egg-based process, is formulated with the adjuvant MF59, an oil-in-water emulsion of squalene oil.
Over the past four years, Selfridges has stopped selling or serving any endangered fish in its food halls and restaurants, or selling shark-based squalene (an organic compound obtained from shark liver oil) in its beauty halls.