start codon


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start codon

n.
A codon, AUG in eukaryotes and either GUG or UUG in bacteria, that signals the initiation of translation and the first amino acid in a polypeptide chain. Also called chain initiation codon.
Translations
codon d’initiation
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References in periodicals archive ?
I discovered that the repeat region is translated in all three reading frames into aggregating dipeptide-repeat (DPR) proteins despite its intronic localization and lack of an ATG start codon.
Tusavims has a potential upstream start codon MSS in a weaker Kozak consensus sequence than MAQ (Figure, panel A), which we selected as the start codon.
All these polymorphisms are numbered relative to the adenine of the translation start codon.
Textbooks of my college era discussed genes in terms of proposed models of cistrons, recons, and mutons; were missing the start codon in charts of the genetic code; and listed "nonsense" for what we know as stop codons (Keeton, 1967).
The first exon is untranslated, and the start codon (AUG) is located at the beginning of exon 2 (1).
This polymorphism, resulting from a T[right arrow]C transition, introduces codon 4 as the start codon resulting in a shorter isoform of the VDR.
The GSTP1 313A[right arrow]G (rs1695), NQO1 609C[right arrow]T (rs1800566), MBL2 codon 54A[right arrow]G (rs1800450), ABCB1 3435C[right arrow]T (rs1045642), MTHFR 677C[right arrow]T (rs1801133), and VDR start codon FokI polymorphism (rs2228570) were genotyped by DNAPrint Genomics (Sarasota, FL) in a multiplex PCR followed by single base extension.
Patients were genotyped for VDR gene polymorphisms at the translation start codon and at the 3'-end region.
Next, each ORF segment was aligned with the start codon beginning at the zero location (ORFs indicated as being in the opposite direction were computed as reverse compliments and aligned).
Primers (200ug/ml) were designed flanking the c1 gene and contained a ribosome binding site upstream of the c1 gene start codon (Figure 3).
The AUG mRNA codon codes for methionine and also acts as the start codon for all proteins.