Although in vivo rodent models may be useful for specific gene inactivation studies (Stokes 2004), human steroidogenesis
during pregnancy differs vastly, making rodent models irrelevant for human studies.
In this study, TAM is the indirect source that increased the estrogen concentration through steroidogenesis
in turn enhanced the liver weight and fat deposition in KN fowl (Tables 2, 3, 4, 5 and 6).
Propiconazole inhibits steroidogenesis
and reproduction in the fathead minnow (Pimephales promelas).
Therefore, in order to get an insight into the possible reproductive-related consequences of daidzein, this study was undertaken to evaluate the effect of daidzein on proliferation and steroidogenesis
of ovine granulosa cells.
However, the effect of BPA exposure on the alteration of ovarian steroidogenesis
in adult animals has not been elucidated.
Included in these programs are assays that cover toxicity pathways involving estrogen, androgen, and thyroid hormone receptors, as well as targets within the steroidogenesis
Unexpectedly, the RIA results showed that daidzein enhanced both basal and hCG-stimulated steroidogenesis
of mouse Leydig cells at concentrations of up to [10.
This disparity in response demonstrates a species-specific sensitivity to phthalate-induced suppression of fetal Leydig cell steroidogenesis
Although functional studies are still needed to better understand the possible influence of VEGF and HIF-1[alpha] on the steroidogenesis
in CL of goat, our observation point towards interesting interactions and a possible regulatory role of VEGF and HIF-1[alpha] on caprine in a paracrine and autocrine manner.