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Does the relief of glucose toxicity act as a mediator in proliferative actions of vanadium on pancreatic islet beta cells in streptozocin diabetic rats?
Streptozocin used in this study was purchased from Sigma Chemicals USA.
Histochemical and biochemical effects of melatonin on pancreatic b-cells on streptozocin treated dia etic rats" Pharmacology, 2: 1-21(2006).
After one week of housing, rats were randomly divided into five groups, each consisting of eight animals; the control group that received no medication and no surgery, the model group (STZ) which received bilateral Intracerebroventricular (ICV) injection of streptozocin (STZ, purchased from Sigma Chemical Co, St.
Table 3: Standard Chemotherapies with Known Nephrotoxicity Risk Carboplatin Cisplatin Cyclophosphamide Gemcitabine Methotrexate Mitomycin Nitrosureas Pemetrexed Streptozocin Vinca alkaloids
Drugs used in this study was Streptozocin (100 mg) Lyophilized powder (from Sigma Aldrich Chemicals Private Limited, Banglore) and Glimepride (1 mg) tablets (from U.
For induction of a human type 2 diabetes-like condition, animals in the "diabetes" and "diabetes + Zn supplementation" groups were fed with a high-fat diet for 35 days, followed by a single intraperitoneal injection (40 mg/kg) of streptozocin (STZ).
Lack of efficacy of streptozocin and doxorubicin in patients with advanced pancreatic endocrine tumors.
Effect of ethanolic leaves extract on blood glucose levels of Streptozocin induced diabetics and normoglycemic wistar rats.
11] The current combination chemothepary, which include streptozocin, 5-FU, cyclophosphamide or doxorubicin, has only genereated short-lasting response in fewer than 10% of patients.
Some chemotherapeutic medications, such as cisplatin, high-dose methotrexate, mithramycin, and streptozocin, have varying degrees of nephrotoxicity and can have severe consequences on the kidneys (Singh, 2012).
Effects of tamoxifen on on the lipid profile of diabetic rats induced by streptozocin.