streptozotocin


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strep·to·zot·o·cin

 (strĕp′tə-zŏt′ə-sĭn)
n.
An antibiotic, C8H15N3O7, produced by an actinomycete (Streptomyces achromogenes), used primarily to treat pancreatic tumors affecting the Islets of Langerhans. Also called streptozocin.

[streptozōticus, epithet of the subspecies from which the antibiotic was isolated (strepto- + Greek zōtikos, maintaining life, pertaining to life; see gwei- in Indo-European roots) + -(my)cin.]
References in periodicals archive ?
They designed the experiment using streptozotocin induced diabetic rats and treated with 200 mg [kg.
The mechanism of alloxan and streptozotocin action in B cells of the rat pancreas.
The effects of desferoxamine and ascorbate on oxidative stress in the streptozotocin diabetic rat.
Modulatory effects of Aloe vera leaf gel extract on oxidative stress in rats treated with streptozotocin.
A condition very similar to type 1 diabetes can be induced in animals by the administration of multiple low doses of streptozotocin (STZ).
Moderate diabetes was induced by single IV injection of streptozotocin (STZ) (Sigma, S-0130) with a dose of 45 mg/kg (Mythili et al.
Effect of D-400, a herbominaral preparation on lipid profile, glycated haemoglobin and glucose tolerance in streptozotocin induced diabetes in rats.
Pioglitazone can ameliorate insulin resistance in low-dose streptozotocin and high sucrose-fat diet induced obese rats.
The well-recognized Streptozotocin (STZ)-induced diabetes model was used to show a significant decrease in glucose levels in the treatment group as compared with the placebo group.
Immuno-unreactive albumin excretion increases in streptozotocin diabetic rats.
In the study, 24 mice received five daffy injections of a diabetes-inducing chemical known as streptozotocin.