succinylcholine


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suc·cin·yl·cho·line

 (sŭk′sə-nĭl-kō′lēn)
n.
A crystalline compound, C14H30N2O4, formed by esterification of succinic acid with choline and used medically to produce brief but complete muscular relaxation during surgical anesthesia.

succinylcholine

(ˌsʌksɪnɪlˈkəʊliːn)
n
a drug, C14H30N2O4, used primarily as a muscle relaxant, produced by the esterization of succinic acid with choline
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.succinylcholine - a muscle relaxant for striated muscle that is used as an adjunct to anesthesia during certain surgical procedures
muscle relaxant - a drug that reduces muscle contractility by blocking the transmission of nerve impulses or by decreasing the excitability of the motor end plate or by other actions
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References in periodicals archive ?
Succinylcholine, commonly used for neuromuscular blockade, can cause PORML with or without features of malignant hyperthermia.
It has been in use since the pharmacological properties of succinylcholine were discovered around 1950 by K.
5-2 mg succinylcholine per kilogram body weight completely abolishes the muscle response to nerve stimulation.
Before the shortage of succinylcholine was resolved earlier this year, shortages of the agent also resulted in postponed surgeries at Veterans Administration Medical Centers.
The action of succinylcholine is to open sodium channels and depolarize the postsynaptic muscle membrane in the same manner as acetylcholine.
This confusion appears to have been created by the use of a muscle relaxant called succinylcholine (also known as Suxamethonium), which, if used in large enough quantities, can cause the heart to stop, making it appear that the victim died of cardiac arrest.
Dubai police last Sunday issued a statement saying the "killers used the drug succinylcholine to sedate al-Mabhouh before they suffocated him" and that "assassins used this method so that it would seem that his death was natural".
On Sunday, Khalfan's deputy, Khamis Mattar al-Mazeina, said in a statement the killers had used the drug succinylcholine "to sedate Mabhouh before they suffocated him.
Summary: According to Dubai Police, the operatives involved in the murder of killing of Hamas commander Mahmoud Al Mabhouh used Succinylcholine to first paralyse and then kill him eventually.
On Sunday, Khalfan's deputy, Khamis Mattar Al-Mazeina, said in a statement that the killers had used the drug succinylcholine "to sedate Mabhouh before they suffocated him.
Rapid onset' The killers used the drug succinylcholine to sedate Mabhouh before they suffocated him, Maj Gen Khamis Mattar al-Mazeina, deputy commander of Dubai's police, said.