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A sulfonamide antibiotic, C10H11N3O3S, that is used especially in combination with trimethoprim to treat bacterial urinary tract infections, other bacterial infections, and infections caused by certain fungi and parasites.


(ˌsʌl fə mɛθˈɒk səˌzoʊl)

an antimicrobial substance, C10H11N3O3S, used to treat urinary-tract and skin infections.
[1955–60; sulfa (nilamide) + meth (yl) + (is)oxazole]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.sulfamethoxazole - a sulfonamide (trade name Gantanol) used to treat infections (especially infections of the urinary tract)
sulfa, sulfa drug, sulfonamide, sulpha - antibacterial consisting of any of several synthetic organic compounds capable of inhibiting the growth of bacteria that require PABA


n sulfametoxazol m
References in periodicals archive ?
There was cross-reactivity with other sulfa antibiotics: Seven of 18 patients with prior sulfamethoxazole allergy reacted to oral challenge with sulfadiazine, and 4 of 9 patients with prior allergy with sulfamethoxazole reacted to challenge with sulfamethazine.
To assess whether antibiotic resistance phenotypes clustered together, antibiograms were assigned using the designation DECLTsRQGA (D for tetracycline, E for erythromycin, C for chloramphenicol, L for clindamycin, Ts for trimethoprim/ sulfamethoxazole, R for rifampicin, Q for ciprofloxacin, G for gentamicin, and A for amikacin).
For instance, most of the polymorphs in the experiment could be made on any of several members of the 436-polymer library, but one of the two new forms of sulfamethoxazole grew on only one polymer.
In patients with normal kidney function, the elimination half-life of sulfamethoxazole is 9 h and that of trimethoprime is 10 h.
Many medication classes contain this chemical entity including sulfonamide antimicrobials (eg, sulfamethoxazole, sulfadiazine, sulfacetamide), carbonic anhydrase inhibitors (eg, acetazolamide, methazolamide), sulfonylureas (eg, glyburide, glipizide), diuretics (eg, hydrochlorothiazide, chlorthalidone, furosemide, bumetanide), uricosurics (eg, probenecid), drugs for inflammatory bowel disease (eg, sulfasalazine), selective serotonin-1 receptor agonists (eg, sumatriptan), and the specific cyclooxygenase-2 inhibitor celecoxib.
In its new drug application to the FDA, Ascent showed in a clinical study with 262 children that Primsol, containing only trimethoprim, was just as effective as the combination trimethoprim and sulfamethoxazole.
AMEX:LCI), a manufacturer of generic pharmaceuticals, today announced that it has commenced marketing Sulfamethoxazole with Trimethoprim single strength (SS) and double strength (DS) tablets.
The patient's medications on admission included zalcitabine, lamivudine, saquinavir, trimethoprim/ sulfamethoxazole, clindamycin, ciprofloxacin, ganciclovir, senna, naproxen, beclomethasone dipropionate, oxymetazoline HCl, morphine, potassium chloride, warfarin, and zolpidem.
The compound, Sulfasim(TM), is designed for the prevention of sulfamethoxazole (SMX) allergy in HIV-infected patients.
sulfamethoxazole plus pyrimethamine tab 500 mg plus 25 mg
Although trimethoprim / sulfamethoxazole (TMP / SMX) is the formal first-line drug therapy for noncomplicated UTI, guidelines suggest substituting a fluoroquinolone in areas where rates of E.