MU: How did you discover that sulforaphane
, isothiocyanate and indoles; produces cancer-fighting enzymes
Broccoli sprouts in particular have the highest concentrations of sulforaphane
recently introduced Brassica Tea, which contains sulforaphane
(SGS), an antioxidant extracted from broccoli.
induces mammalian detoxification enzyme activity and inhibits early tumor growth in rodent models.
A series of studies at Johns Hopkins University demonstrate that Brassica vegetables are rich sources of phase 2 inducers and identify isothiocyanate sulforaphane
as the principal phase 2 inducer in broccoli extracts.
New research has found that the tiny shoots of sprouting broccoli contain a powerful blocking agent known as sulforaphane
But it also contains sulforaphane
, which reportedly has potent anti-cancer properties (see "Quick Studies," June 1992).
What this means to patients: Consumption of sulforaphane
in broccoli may provide validated intervention to prevent progression of prostate cancer in active surveillance patients, alleviating overtreatment.
Evgen Pharma chief executive Dr Stephen Franklin said: "The anti-cancer and anti-inflammatory properties of sulforaphane
are well-documented and are supported by a wealth of published peer-reviewed scientific papers.
Researchers from Oregon State University and the Texas A&M Health Science Center report in the journal Oncogenesis a potential benefit for sulforaphane
in treating metastatic prostate cancer.
The molecular mechanism of action of aspirin, curcumin and sulforaphane
combinations in the chemoprevention of pancreatic cancer.