sulindac


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Noun1.sulindac - a nonsteroidal anti-inflammatory drug (trade name Clinoril)
nonsteroidal anti-inflammatory, nonsteroidal anti-inflammatory drug, NSAID - an anti-inflammatory drug that does not contain steroids; "NSAIDs inhibit the activity of both Cox-1 and Cox-2 enzymes"
ketone - any of a class of organic compounds having a carbonyl group linked to a carbon atom in each of two hydrocarbon radicals
References in periodicals archive ?
For the study, the researchers separated 52 mice with colon cancer tumors into three groups, including a control group and groups that were fed either the grape compounds or sulindac, an anti-inflammatory drug.
Photoprotective effects of sulindac against ultraviolet B-induced phototoxicity in the skin of SKH-1 hairless mice.
For the animal study, they separated 52 mice with colon cancer tumors into three groups, including a control group and groups that were fed either the grape compounds or sulindac, an anti-inflammatory drug, which was chosen because a previous study showed it significantly reduced the number of tumors in humans.
g) lbuprofen, aceclofenac, acemetacin, dexibuprofen, dexketoprofen, diclofenac sodium, diflunisal, etodolac, fenbufen, fenoprofen, flurbiprofen, ibuprofen, indometacin, ketoprofen, mefenamic acid, meloxicam, nabumetone, naproxen, piroxicam, sulindac, tenoxicam, tiaprofenic acid, diclofenac/misoprostol.
5) In 2012, Castelsague, et al, conducted a meta-analysis of 28 studies and found that naproxen (relative risk 4-5) has a higher risk of gastrointestinal events when compared to aceclofenac, celecoxib and ibuprofen (RR<2), and rofecoxib, sulindac, diclofenac, meloxicam, nimesulide and ketoprofen (RR= 2<X< 4).
Although all NSAIDs can affect kidney function, NSAIDs with a quick onset and short half-life, such as ibuprofen, can exhibit nephrotoxic effects in a matter of days compared to NSAIDs with a longer half-life, like piroxicam and sulindac (Whelton, 1999).
Loss of GDF-15 abolishes sulindac chemo-prevention in the ApcMin/+ mouse model of intestinal cancer.
Difluoromethylornithine plus sulindac for the prevention of sporadic colorectal adenomas: a randomized placebo-controlled, double-blind trial," Cancer Prevention Research, vol.
Non-steroidal anti-inflammatory agents: phenylbutazone, indomethacin, ibuprofen, sulindac and aspirin.
Combination treatment with arsenic trioxide and sulindac augments their apoptotic potential in lung cancer cells through activation of caspase cascade and mitochondrial dysfunction.
NSAID classification Non-selective inhibition Acetic acid Proprionic acid Fenamate derivatives derivatives derivatives * Diclofenac * Fenoprofen * Meclofenamate * Etodolac * Flurbiprofen * Mefenamic acid * Indomethacin * Ibuprofen * Sulindac * Ketoprofen * Tolmetin * Naproxen * Oxaprozin Naphthyl alkanone Salicylates * Nabumetone * Aspirin * Diflunisal * Choline magnesium trisalicylate * Salicylate Enolic acid derivatives * Piroxicam * Meloxicam Selective COX-2 inhibition * Celecoxib * Rofecoxib Table 9.