suppressor T cell

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suppressor T cell

n.
A T cell that reduces or suppresses the immune response of B cells or of other T cells to an antigen.

suppressor T cell



n.
a T cell capable of inhibiting the activity of B cells and other T cells.
Also called T suppressor cell.
References in periodicals archive ?
Huang, "Up-regulated myeloid-derived suppressor cell contributes to hepatocellular carcinoma development by impairing dendritic cell function," Scandinavian Journal of Gastroenterology, vol.
A new research report suggests that the drug may have significant anti-cancer properties as they interfere with the function of myeloid derived suppressor cell that is known to reduce the body's ability to fight tumors by interfering with the activity of cells.
T-suppressor cell function was noted during MS attacks with suppressor cell function restored during remissions.
Results: CD4 and CD8 counts and CD4:CD8 ratios were normal in all eight patients, in contrast to the suppressor cell proliferation and low helper-suppressor ratios that have been previously reported in other patients with B-cell chronic lymphocytic leukemia.
Ash from burned residual oil, a viscous boiler fuel, proved even more potent at triggering suppressor cell suicides.
It was just over 10 years ago that people with multiple sclerosis were first discovered to be deficient in their suppressor cell function compared with healthy people.
GCN2 is a myeloid-derived suppressor cell target that works downstream of IDO and arginase.
Differential sensitivity of T suppressor cell expression to inhibition by histamine type 2 receptor antagonists.
In the fourth trial, patients were pretreated with cylophosphamide to diminish suppressor cell activity.
Aminex Therapeutics is focused on discovery, development, and commercialisation of suppressor cell modulators (SCM), a new class of small molecule cancer immunotherapies which enable the immune system to attack cancer by regulating myeloid-derived suppressor cells.
It could be," says Levy, "that the suppressor cell, by blocking the virus, would also prevent the production of autoantibodies.
Results reveal that the Liver-X Receptor/Apolipoprotein E (LXR/ApoE) pathway regulates anti-tumor immunity via effects on myeloid-derived suppressor cells (MDSCs), an immunosuppressive cell population that have been found to be circulating at high levels in cancer patients who are also commonly found to be non-responders to immunotherapy.