suramin


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Related to suramin: Melarsoprol

suramin

(ˈsɜːrəmɪn)
n
1. (Veterinary Science) a drug used to treat trypanosomiasis
2. (Pharmacology) a drug used to treat trypanosomiasis
Translations

suramin

n suramina
References in periodicals archive ?
Scientists in California have found that suramin reduces the symptoms of autistic behaviour in boys aged between five and 14.
To observe the efficacy of the various drugs, Thirty Two positive cases were selected and divided into four groups, Group A was treated with Suramin, Group B with Isometamidium chloride, group C was treated with the Diminazine di aceturate and group D was kept as control.
30 [micro]M compared to suramin (MIC = 10 [micro]M) as a positive reference (Igoli et al.
Two matriptase activation inducers such as lysophospholipid-derivative, sphingosine 1-phosphate (S1P), and polyanionic compound, suramin, were found to act cell-type specifically [13].
Suramin inhibits bFGF induced endothelial cell proliferation and angiogenesis in the chick chorioallantoic membrane.
Anti-adhering and anti-migratory compounds ilomastat (a matrix metalloproteinase inhibitor), naphtyl urea suramin, [44] salmosin (a disintegrin), [45] mibefradil (Ca- channel inhibitor), [46] RGD peptide, EDTA, [47] and coating an acrylic IOL surface with MPC polymer; [48]
Another well-known drug, suramin, has been medically used for the treatment of African sleeping sickness since early 20th century and is an ATP mediator.
Naviaux, MD tested the effect of suramin, used to treat trypanosomiasis or African sleeping sickness, a parasitic disease and found that suramin blocked the extracellular signaling pathway used by ATP and other mitokines in a mouse model of autism spectrum disorder (ASD), ending the cell danger response and related inflammation.
Drug-induced lipidosis and vortex keratopathy is produced by amphiphilic medications such as amiodarone, chloroquine, suramin, clofazimine, etc16.
The drug, suramin, targets a cellmessaging system that produces a metabolic response to stress.
Suramin was discovered in 1921 and used in the first stage treatment and prophylaxis of African trypanosomiasis.