suramin


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Related to suramin: Melarsoprol

suramin

(ˈsɜːrəmɪn)
n
1. (Veterinary Science) a drug used to treat trypanosomiasis
2. (Pharmacology) a drug used to treat trypanosomiasis
Translations

suramin

n suramina
References in periodicals archive ?
Naviaux, MD tested the effect of suramin, used to treat trypanosomiasis or African sleeping sickness, a parasitic disease and found that suramin blocked the extracellular signaling pathway used by ATP and other mitokines in a mouse model of autism spectrum disorder (ASD), ending the cell danger response and related inflammation.
Arsenicals (melarsoprol) pentamidine and suramin in the treatment of human African trypanosomiasis.
The drug, suramin, targets a cell messaging system that produces a metabolic response to stress.
The drug, suramin, targets a cellmessaging system that produces a metabolic response to stress.
2005) The use of suramin, an antifibrotic agent, to improve muscle recovery after strain injury.
Suramin was discovered in 1921 and used in the first stage treatment and prophylaxis of African trypanosomiasis.
A 100-mg test dose of suramin was well tolerated by the patient; however, the first full treatment dose was complicated by circulatory collapse and bronchoconstriction, which required administration of hydrocortisone and chlorphenamine and immediate discontinuation of the suramin infusion.
1) It is less effective than suramin against Trypanosoma brucei rhodensiense and is also an ineffective treatment for the encephalitic stage of trypanosomiasis.
Antifibrotic effects of suramin in injured skeletal muscle after laceration.
To inhibit fibrosis formation following severe injury, attributed in large part to the secretion of transforming growth factor (TGF)- [beta] 1 [10], researchers have investigated the administration of TGF-[beta]1 specific inhibitors, such as relaxin [11], decorin [12], and suramin [13-15].
12) effective against microfilaria Adjunctive doxycycline sterilises female worm Add systemic steroids in cases of eye involvement Suramin for adult worms Loiasis (Fig.
14] Circulating heparin-like activity has been reported in a patient with metastatic adrenocortical carcinoma, undergoing treatment with the anti-protozoal agent suramin,[sup.