A panel of syngeneic
MLC with a defined and a genetically malleable battery of mutated oncogenes would allow more physiologically relevant studies, would help accelerate research and drug discovery in the field, and would generate substantial interest in the academia and the industry.
The portable and interactive data platform incorporates encompassing information of more than 1,000 cancer patient-derived xenograft (PDX), human cancer cell-derived xenograft (CDX), and syngeneic
mouse tumor models.
The Global Stem Cell Market can be segmented on the basis of Service (Stem Cell Banking, Stem Cell Acquisition & Testing and Cryopreservation), Therapeutic Applications (Regenerative Medicine, Neurological Disorders, Orthopedic Treatments, Oncology, Diabetes, Injuries & Wounds and Cardiovascular Disorders), Treatment Types (Allogeneic Stem Cell Therapy, Autologic Stem Cell Therapy, Syngeneic
Stem Cell Therapy) and Geography (North America, Europe, Asia Pacific, Middle East & Africa, Latin America and Rest of the World).
Roxatidine- and cimetidine-induced angiogenesis inhibition suppresses growth of colon cancer implants in syngeneic
The donor was immunized with MAGE-A3 protein, and primed donor cells collected after immunization were transferred to her identical twin after syngeneic
stem cell transplant, followed by repeated patient immunizations.
Herb and Bert had found that the intense inflammatory response to local injection of BCG could produce regression of syngeneic
hepatoma transplants growing on the flanks of guinea pigs, eliminate regional lymph node metastases, and induce tumor-specific immunity (9).
The B16-F10 cell line (established from a primary custaneous mouse C57BL/6 melanoma) is a murine melanoma variant and highly metastatic to the lungs of syngeneic
C57BL/6 mice (Eisenthal et al.
Pharmacological ascorbic acid suppresses syngeneic
tumor growth and metastases in horrnone-refractory postate cancer.
We have previously shown that inhibition of leptin signaling with pegylated leptin peptide receptor antagonist 2 (PEG-LPrA2) negatively impacted on the growth of mouse syngeneic
and human breast cancer xenografts hosted by SCID mice, PEG-LPrA2 effects paralleled a significant reduction of VEGF/VEGFR2 levels.
Inhibitory effect of Cordyceps sinensis on spontaneous liver metastasis of Lewis lung carcinoma and B16 melanoma cells in syngeneic
bone marrow transplantation is rare in patients with severe aplastic anemia and usually requires pre-transplant conditioning to provide engraftment.
Cultured splenocytes were transferred into syngeneic
mice, and 4 days after the transfer, the recipient mice were challenged with RW.