Although we try to promote the growth rate and the amount of axons, inefficient accurate docking between nerve and target organ
leads to poor functional recovery or malfunction.
If undiagnosed, high blood pressure can lead to"possible target organ
damage in the brain, eyes, heart and kidneys," said study leader Dr.
The committee strongly recommended the routine performance of ambulatory BP monitoring in patients with high-risk conditions, such as diabetes, secondary hypertension, or renal disease, to look for abnormal circadian BP patterns that might point to an increased risk of target organ
Even more alarming, it cautioned that "Screening is not done systematically, and the diagnosis is often made at a late stage when target organ
damage has already happened.
An important indicator of hypertensive vascular disease in adults is the target organ
damage (TOD) caused by elevated blood pressure.
To assess safety, it is important to know if cells have engrafted into non-target organs
so that possible adverse effects can be monitored over time; and to assess efficacy, it is crucial to know what proportion of cells reach the target organ
, for how long they persist, and whether they ameliorate injury.
The extent of target organ
damage--and you could say that aortic stenosis is actually target organ
damage, like atrial fibrillation or left ventricular hypertrophy--warrants a different level of blood pressure.
Moreover, Altogen Labs has developed methods to prevent siRNA degradation in serum (including both chemical modification and encapsulation of siRNA), increase delivery efficiency to the target organ
, and produce strong tissue-targeted functional effects induced by siRNA in vivo.
Sections 3-4 cover target organ
toxicity and other systemic effects, with sections 5-6 addressing damage to the natural environment and then circling back to discuss toxin pharmacology and metabolism.
The microcapsules resist low pH levels, making it possible for them to pass through the stomach without opening and deliver the viable probiotics directly to the intestine, which is the target organ
We conclude that the mink uterus expresses the insulin receptor gene, and is a target organ
for the hormone.
Clonal expansion of EBV-infected autoreactive B cells in the target organ