taxane


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tax·ane

 (tăk′sān′)
n.
Any of a class of anticancer drugs, such as paclitaxel, obtained from yew trees or synthesized, that inhibit the division of tumor cells by binding to and interfering with the action of microtubules.

[New Latin Tax(us), yew genus (from Latin taxus, yew) + -ane.]
References in periodicals archive ?
The company's initial focus is on the development of tesetaxel, an investigational, orally administered chemotherapy agent belonging to the taxane class.
Methods: We included 30 patients who received at least 6 cycles of taxane regimen for metastatic mPC in the present study.
1% of those receiving a taxane experienced hair preservation, compared with 21.
TAXYNERGY trial shows that early taxane switch may improve PSA response rate and that androgen receptor nuclear localization may indicate taxane sensitivity/resistance
It is an orally available tubulin targeting agent that has demonstrated efficacy in preclinical studies against hormone sensitive, castration resistant, as well as taxane resistant prostate cancer.
Objective: SIVIDON established a prototype diagnostic assay - the ChemoPredict test - to stratify high-risk breast cancer patients and to help in deciding whether to treat the patient with standard anthracycline-based chemotherapy without taxane or taxane-containing regimens.
Results: Oral administration of taxane fractions isolated from Taxus chinensis (containing 17.
Prior therapy should have included an anthracycline and a taxane in either the adjuvant or metastatic setting, unless patients were not suitable for these treatments.
Tesetaxel is the leading oral taxane in clinical development.
Chemotherapy: The patients in the study were receiving either platinum or taxane chemotherapy.
In final guidance, the National Institute for Health and Clinical Excellence (Nice) said it did not recommend Avastin (bevacizumab) for the treatment of advanced breast cancer when used in combination with a taxane (a type of chemotherapy).
In final guidance, the National Institute for Health and Clinical Excellence said it did not recommend Avastin for the treatment of advanced breast cancer when used in combination with a taxane (a type of chemotherapy).