tertiary structure


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Related to tertiary structure: quaternary structure, tertiary structure of protein

tertiary structure

n.
The complete three-dimensional structure of all the atoms in a protein or nucleic acid, consisting of the arrangement of the secondary structure into patterns such as folds and supercoils.
References in periodicals archive ?
Determination of secondary and tertiary structure, ways of probing protein-protein interactions, and more complicated topics such as protein modification, microarrays, and other applications round out the book.
A protein's overall antioxidant activity can be increased by disruption of its tertiary structure to increase the solvent accessibility of amino acid residues that can scavenge free radicals and chelate prooxidative metals.
Aa], has provided insights into the DAT's tertiary structure (1).
The entire pipe cleaner model (containing both pencil binding and handle domains) can be considered analogous to a tertiary structure.
Polygonatum cyrtonema lectin [PCL], Ophiopogon japonicus lectin [OJL] and Liparis noversa lectin [LNL]), were reported to possess a similar tertiary structure with three mannose-binding sites and a close phylogenetic relationship.
Modeling of the tertiary structure indicated that CtCVNH is an elongated, largely [beta]-sheet protein that displays internal two-fold pseudosymmetry.
Proteins come in three dimensions, and their structure is generally imposed by the secondary and tertiary structure of the peptide chain.
Anticalins have several additional advantages over conventional antibodies due to their small size (20 kDa), robust tertiary structure and straight composition that confer high solubility, predictable stability and bacterial manufacturability.
It becomes possible to estimate molecular mass for single-chain species only when the protein calibrators and analytes possess the same tertiary structure, as occurs when denaturing/disulfide-reducing solvents are used, for example (10).
A different scenario is that New Zealand may move towards a dichotomous tertiary structure of teaching universities (mostly undergraduate) and research universities (graduate).
To determine whether the disulfide bonds contribute to the secondary or tertiary structure of this protein, circular dichroism measurements were performed in the presence or absence of a reducing agent (dithiothreitol).
Circular dichroism is primarily used in determining the structure of proteins, particularly the secondary structure, though analysis of the tertiary structure is also possible.