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thiouracil

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thi·o·u·ra·cil  (th-yr-sl)
n.
A white crystalline compound, C4H4N2OS, that interferes with the synthesis of thyroxine, used to reduce the action of the thyroid gland, especially in the treatment of hyperthyroidism.
thiouracil [ˌθaɪəʊˈjʊərəsɪl]
n
(Medicine / Pharmacology) a white crystalline water-insoluble substance with an intensely bitter taste, used in medicine to treat hyperthyroidism; 2-thio-4-oxypyrimidine. Formula: C4H4N2OS
[from thio- + uracil (uro-1 + ac(etic) + -il -ile)]
ThesaurusLegend:  Synonyms Related Words Antonyms
Noun1.thiouracil - depresses the function of the thyroid gland
organic compound - any compound of carbon and another element or a radical
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When relative efficacy was compared with that of propyl thiouracil (PTU), a standard antithyroidic drug, experimental seed extract appeared to be more effective.
Annona squamosa seed extract in the regulation of hyperthyroidism and ... by Panda, S.; Kar, A. / Phytomedicine: International Journal of Phytotherapy & Phytopharmacology
Similar thyroid hyperplasia has been observed after treatment of fish with goitrogens such as thiourea and thiouracil that inhibit coupling and formation of iodotyrosines in the thyroid.
Effects of ammonium perchlorate on thyroid function in developing ... by Brown, J. Anne / Environmental Health Perspectives
Because PBDEs have the ability to interfere with thyroid hormone (TH) homeostasis, we included a reference group for TH-mediated effects by adding the goitrogen 6-n-propyl thiouracil (PTU) in the drinking water of pregnant females.
Developmental exposure to low-dose PBDE-99: effects on male fertility ... by Chahoud, Ibrahim / Environmental Health Perspectives
 
 
 
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