Due to thrombocytosis
(457-593 x 109/L), bone marrow aspiration was performed, which revealed hyperplasia of mature megakaryocytes and JAK2 V617F mutation.
12] Platelet large cell ratio (P-LCR) is significantly decreased in thrombocytosis
and increased in thrombocytopenia; P-LCR inversely related to platelet count and directly related to PDW and MPV.
Pathogenesis and causes of hyperkalemia Pathogenesis of Causes of hyperkalemia hyperkalemia False Hyperkalemia Hemolysis Tight turnstile Thrombocytosis
Leukocytosis Impaired elimination of ARF, CRF potassium Pseudohypoaldosteronism, hypoaldosteronism, and congenital adrenal hyperplasia Medications (ACEI, ARB, NSAI) Mannitol Drugs interfering with renal potassium excretion (amiloride, spironolactone, and triamteren) Increased shift of Trauma potassium from intra Burn injury to extracellular space Rhabdomyolysis, tumorlyis, hemolysis, and after massive transfusion Acidosis Hyperkalemic periodic paralysis Hyperglisemia Succinylcholine Excessive intake ARF: Acute renal failure, CRF: Chronic renal failure, ACEI: Anjiotensin-converting-enzyme inhibitor, ARB: Anjiotensin
Taking in consideration that the emergence of thrombocytosis
in inflammation, including JIA, is primarily the consequence of IL-1, tumor necrosis factor alpha and IL-6, [44,45] while IL-17A stimulates the production and displays the synergetic effects with these cytokines,  the correlation of IL-17A levels and thrombocyte count could be expected, although it has not been proved in our study.
Patients with a blood test showing thrombocytosis
should be screened for occult cancer.
Blood cell count was within normal values, which is in accordance with cutaneous mastocytosis; in systemic mastocytosis, blood cell counts may reveal anemia, thrombocytopenia, thrombocytosis
, leukocytosis, and eosinophilia.
Test characteristics, including sensitivity, specificity, and concordance rate with the reference method of the evaluated automated counts at the thrombocytopenia and thrombocytosis
thresholds, were also analyzed.
Though their function is important, too many of these platelets can lead to a condition known as thrombocytosis
Around two per cent of people over 40 -- up to half a million people in the UK -- have a raised blood platelet count -- known as thrombocytosis
Dehydration and surrenal deficiency were considered since thrombocytosis
was present in addition to hyponatremia and hyperpotassemia.
Also, laboratory liver tests are in accordance with paraneoplastic syndrome (hypoglicemia, hypocalcemia, erythrocytosis, thrombocytosis
Known diseases were essential thrombocytosis
, paroxysmal atrial fibrillation, and hypercholesterinemia.