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Related to thromboplastin time: Thrombin time


A complex of protein and phospholipids that is found in tissues and platelets and facilitates blood clotting by converting prothrombin to thrombin.


(Biochemistry) any of a group of substances that are liberated from damaged blood platelets and other tissues and convert prothrombin to thrombin. Also called: thrombokinase


(ˌθrɒm bəˈplæs tɪn)

a lipoprotein in the blood that converts prothrombin to thrombin.
Also called throm•bo•ki•nase (ˌθrɒm boʊˈkaɪ neɪs, -ˈkɪn eɪs)
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.thromboplastin - an enzyme liberated from blood platelets that converts prothrombin into thrombin as blood starts to clot
clotting factor, coagulation factor - any of the factors in the blood whose actions are essential for blood coagulation
References in periodicals archive ?
A basic initial work-up includes a full blood count with peripheral blood smear review, prothrombin time/international normalised ratio and a partial thromboplastin time.
The partial thromboplastin time has been the gold standard for monitoring.
Prothrombin time and activated partial thromboplastin time, albumin levels and alpha-1 antitrypsin value checked for liver failure were normal.
Institutions were asked to provide retrospective data related to the first plasma transfusion episode for 40 adult patients: the number of plasma units prepared for the patient, the number of plasma units transfused, the indication(s) for transfusion (chosen from a list), pretransfusion and posttransfusion coagulation test results (prothrombin time [PT], international normalized ratio [INR], activated partial thromboplastin time [aPTT]), and occurrence and type of transfusion reaction.
Prolonged Prothrombin Time, Activated Partial Thromboplastin Time and a normal platelet count pointed towards a disorder of coagulation.
5 s aPTT 128s 25-35 s Fibrinogen 495 mg/dL 175-400 mg/dL Factor II 5% 50%-150% Factor V 98% 50%-150% Factor VII 10% 50%-150% Factor IX 8% 50%-150% (a) PT, prothrombin time; aPTT, activated partial thromboplastin time.
Previous studies have shown that in patients with SFTS, blood coagulation parameters are prolonged, as characterized by activated partial thromboplastin time and thrombin time (9,10).
Material and Methods: Patients referred to the Nephrology Department for kidney biopsy were considered for inclusion in the study provided they did not have any contraindications to the procedure and had a normotensive state with BP less than 130/90 mm Hg and a normal coagulation profile including partial thromboplastin time, prothrombin time, bleeding time and platelet count.
The activated partial thromboplastin time (APTT) is a clot-based test of the intrinsic and common coagulation pathways.
lucidum in-vitro based on prothrombin time (PT) and activated partial thromboplastin time (aPTT).
At that time, she was admitted to the hospital, where lab tests showed prolonged prothrombin time (PT), international normalized ratio (INR), activated partial thromboplastin time (aPTT), and elevated D-dimer level, with a normal platelet count.
Laboratory results on hospitalization revealed anemia and elevated levels of fibrin degradation products (FDP), D-dimer, and fibrinogen (FIB), but prothrombin time (PT) and activated partial thromboplastin time (aPTT) were within the normal range (Table 1).