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A complex of protein and phospholipids that is found in tissues and platelets and facilitates blood clotting by converting prothrombin to thrombin.


(Biochemistry) any of a group of substances that are liberated from damaged blood platelets and other tissues and convert prothrombin to thrombin. Also called: thrombokinase


(ˌθrɒm bəˈplæs tɪn)

a lipoprotein in the blood that converts prothrombin to thrombin.
Also called throm•bo•ki•nase (ˌθrɒm boʊˈkaɪ neɪs, -ˈkɪn eɪs)
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.thromboplastin - an enzyme liberated from blood platelets that converts prothrombin into thrombin as blood starts to clot
clotting factor, coagulation factor - any of the factors in the blood whose actions are essential for blood coagulation
References in periodicals archive ?
Optimization of the dilute prothrombin time for the detection of the lupus anticoagulant by use of a recombinant tissue thromboplastin.
PRINCIPLE: Tissue thromboplastin in the presence of calcium activates the extrinsic pathway of human blood coagulation mechanism.
The occurrence of thrombosis can be explained either by an excessive activation of the coagulation cascade on the external pathway, secondary to an increased tissue thromboplastin level or by the direct effect of the electric current on the vascular branches with extensive endothelial lesions.