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thromboplastin
(redirected from tissue thromboplastin)

    Also found in: Medical, Encyclopedia 0.01 sec.
throm·bo·plas·tin  (thrmb-plstn)
n.
A protease that converts prothrombin to thrombin in the early stages of blood clotting. Also called thrombokinase.
thromboplastin [ˌθrɒmbəʊˈplæstɪn]
n
(Life Sciences & Allied Applications / Biochemistry) any of a group of substances that are liberated from damaged blood platelets and other tissues and convert prothrombin to thrombin Also called thrombokinase
ThesaurusLegend:  Synonyms Related Words Antonyms
Noun1.thromboplastin - an enzyme liberated from blood platelets that converts prothrombin into thrombin as blood starts to clot
factor III, thrombokinase
clotting factor, coagulation factor - any of the factors in the blood whose actions are essential for blood coagulation
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Abnormalities of local tissue procoagulation and fibrinolysis have been described in sarcoidosis; namely, enhanced tissue factor pathway activity, increased tissue thromboplastin activity, diminished plasminogen activator activity, increased factor VII activity, decreased protein C activation, and increased thrombin-activatable fibrinolysis inhibitor.
Multiple venous thromboses in a young man with sarcoidosis: is there ... by Marik, Paul E. / Southern Medical Journal
In our lab, we came across a challenging situation when we switched to a new (for us) recombinant human tissue thromboplastin, which has an International Sensitivity Index (ISI) of around 1.
Under the blue top: part II fine-tune your ISIs by Midyett, Roy / Medical Laboratory Observer
In the 1998 revision (H21-A3), CLSI removed the recommendation to use a discard tube when drawing PT (prothrombin time) and APTT (activated partial thromboplastin time) tests, since studies showed tissue thromboplastin did not affect results when the sodium citrate tube was the first or only tube drawn using a tube holder.
Specimen-collection standards complete major revisions by Ernst, Dennis J.; Szamosi, Diane I. / Medical Laboratory Observer
 
 
 
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