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tolbutamide

   Also found in: Medical, Encyclopedia, Wikipedia 0.01 sec.
tol·bu·ta·mide  (tl-byt-md)
n.
A white powder, C12H18N2O3S, that lowers the level of sugar in the blood and is used in the treatment of diabetes.
[tol(u) + but- + amide.]
tolbutamide [tɒlˈbjuːtəˌmaɪd]
n
(Medicine / Pharmacology) a synthetic crystalline compound administered orally in the treatment of diabetes to lower blood glucose concentrations. Formula: C12H18N2O3S
[from tol(uyl) + but(yric acid) + amide]
ThesaurusLegend:  Synonyms Related Words Antonyms
Noun1.tolbutamide - sulfonylurea; an oral antidiabetic drug (trade name Orinase) used in the treatment of adult-onset diabetes mellitus
Orinase
sulfonylurea - antidiabetic consisting of any of several drugs that reduce the level of glucose in the blood; used to treat diabetes mellitus
hypoglycaemic agent, hypoglycemic agent - any of various agents that decrease the level of glucose in the blood and are used in the treatment of diabetes mellitus
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More recommended oral hypoglycemic drugs Such as tolbutamide, chlorpropamide, tolazamide, acetohexamide, glyburide, glipizide, glimepiride, repaglinide, or meglitonide may be prescribed to increase insulin production by the pancreas, if exercise and diet do not lower glucose levels sufficiently.
Diabetes Causes, Prevention and Treatment Part 2 by john daniel rivera / Health, general community
Normal rats, having undergone overnight fasting, received a single dose of 100 mg/kg or 200 mg/kg, while control groups received a placebo or tolbutamide 250 mg/kg.
Mucuna pruriens and diabetes by Finney-Brown, Tessa / Australian Journal of Medical Herbalism
The leaves and roots of the plant showed antidiabetic activity comparable to tolbutamide (Brahmachari and Augusti, 1963).
Antidyslipidemic activity of polyprenol from Coccinia grandis in ... by Singh, Geetu; Gupta, Prasoon; Rawat, Preeti; Puri, Anju; Bhatia, Gitika; Maurya, Rakesh / Phytomedicine: International Journal of Phytotherapy & Phytopharmacology
 
 
 
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