tonic-clonic


Also found in: Thesaurus, Medical, Legal, Encyclopedia, Wikipedia.
Related to tonic-clonic: grand mal seizure, Clonic seizure

ton·ic-clon·ic

(tŏn′ĭk-klŏn′ĭk)
adj. Medicine
Both tonic and clonic.
References in periodicals archive ?
Perampanel is indicated for the adjunctive treatment for partial onset seizures, with or without secondarily generalised seizures, in patients with epilepsy aged 12 years and older and for adjunctive treatment of primary generalised tonic-clonic seizures, in patients with idiopathic generalised epilepsy.
For this year's AES meeting, poster presentations will be given on 22 abstracts with highlights including additional and pooled analyses on the results of global Phase III clinical studies on primary generalized tonic-clonic (PGTC) seizures in patients with generalized epilepsy (Study 332) and on partial-onset epilepsy (Study 304, Study 305, Study 306), as well as the results of a Phase III clinical study on partial-onset epilepsy conducted in Asia including Japan.
Clinical Laboratory Evaluation and Treatment-Emergent Adverse Events Related to Cardiac, Hepatic and Renal Disorders; Perampanel PGTC Phase III Study This analysis evaluated laboratory tests and treatment-emergent adverse events related to these tests, as well as cardiac-, hepatic- and renal-related treatment-emergent adverse events, in subjects aged 12 years or older enrolled in a primary generalized tonic-clonic seizure Phase III study.
In Japan, new drug applications were submitted in July 2015 seeking the approval of perampanel as an adjunctive therapy for partial-onset and generalized tonic-clonic seizures based on the results of Study 335 and other studies.
He began to suffer tonic-clonic fits, which became increasingly regular and longer lasting.
Indicated for adjunctive therapy for partial onset seizures in adults and children; monotherapy in partial onset seizures, monotherapy for generalized seizures associated with Lennox-Gastault syndrome and tonic-clonic seizures in generalized epilepsy
He had first experienced a tonic-clonic seizure nine years before this admission, after he witnessed the murder of a friend.
Children who have tonic-clonic seizures often pass out, get stiff, and then have jerking movements.
She suffered a tonic-clonic seizure en route to the emergency department, which was treated with rectal diazepam (intravenous access could not be obtained).
JME is quite a frequent disease in Qatar as it is in Europe, America, Indian subcontinent and Africa, and most patients with this disease have tonic-clonic seizures and many also have absence seizures," Dr Mesraoua explained.
An additional study offered preliminary insight into the antiepileptic drug's (AED) safety as adjunctive therapy for patients with primary generalized tonic-clonic seizures (PGTCS), UCB said.
The worst are called tonic-clonic seizures when she turns blue and stops breathing.