tophus


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Related to tophus: hyperuricemia, gout

to·phus

 (tō′fəs)
n. pl. to·phi (-fī)
1. A deposit of urates in the skin and tissue around a joint or in the external ear, occurring in gout. Also called chalkstone.
2. A concretion of mineral salts and organic matter deposited on the surface of the teeth.

[Latin tōphus, tufa.]

tophus

(ˈtəʊfəs)
n, pl -phi (-faɪ)
(Pathology) pathol a deposit of sodium urate in the helix of the ear or surrounding a joint: a diagnostic of advanced or chronic gout. Also called: chalkstone
[C16: from Latin, variant of tōfus tufa, tuff]
tophaceous adj

to•phus

(ˈtoʊ fəs)

n., pl. -phi (-fī).
a calcareous concretion formed in the soft tissue about a joint, in the pinna of the ear, etc., esp. in gout.
[1545–55; < Latin tōphus, tōfus tufa]
to•pha•ceous (təˈfeɪ ʃəs) adj.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.tophus - a deposit of urates around a joint or in the external eartophus - a deposit of urates around a joint or in the external ear; diagnostic of advanced or chronic gout
urate - a salt of uric acid
2.tophus - an incrustation that forms on the teeth and gumstophus - an incrustation that forms on the teeth and gums
crust, encrustation, incrustation - a hard outer layer that covers something
Translations

to·phus

n. tofo.
1. depósito de sal de ácido úrico en los tejidos, gen. visto en casos de gota;
2. cálculo dental.

tophus

n (pl -phi) tofo
References in periodicals archive ?
Of those with a tophus at baseline, 6 (16%) of 37 of the control/DE group and 4 (13%) of 31 of the DE/ DE group had complete resolution of all tophi between months 12 and 24.
We report the case of 32-year-old male who had a painful knee due to tophus formation in the interosseous area of the bipartite patella.
This report presents a unique case of extension loss due to a single, isolated intra-articular gouty tophus.
Although tophus is generally anticipated in the late period, there are reports in literature of presentation with tophi even on the first attack.
The premier diagnostic test for gout is the identifying MSU crystals in synovial fluid cells or in a tophus (a lump of urate crystals in soft tissue, such as an elbow).
They underwent ultrasound examinations (most commonly of the knees, metatarso-phalangeal joints, and ankles) and were deemed to have a "positive test" if at least one of three signs appeared: a "double contour" sign, tophus, or a "snowstorm" appearance.
A 58-year-old male patient with 20-year history of gout presented with large, painful, ulcerated tophus with necrosis of the overlaying skin on the first interphalangeal joint (IPJ) of right foot.
If you suffer chronic or frequent attacks, or more than one joint is affected, or you develop kidney stones or a tophus (large lumps of crystals), you may need medication to reduce your uric acid production.
9,20) Aspiration of the joint or tophus and demonstrating MSU crystals with polarizing microscopy is highly sensitive and specific for the diagnosis of gout and is the gold standard.
Sufficient clinical criteria (if met, can classify as gout; then step 3 is not necessary): presence of MSU crystals in a symptomatic joint or bursa or the presence of tophus.
In patients with a long evolution of hyperuricemia and many acute attacks, gout can also be found in a chronic form, having as a main manifestation the gouty tophi (tophus = a friable and porous stone), a tophus being a deposit of small monosodium urate crystals surrounded by inflammatory cells.