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tophus

   Also found in: Medical, Encyclopedia, Wikipedia 0.03 sec.
to·phus  (tfs)
n. pl. to·phi (-f)
1. A deposit of urates in the skin and tissue around a joint or in the external ear, occurring in gout. Also called chalkstone.
2. A concretion of mineral salts and organic matter deposited on the surface of the teeth.

[Latin tphus, tufa.]

tophus [ˈtəʊfəs]
n pl -phi [-faɪ]
(Medicine / Pathology) Pathol a deposit of sodium urate in the helix of the ear or surrounding a joint: a diagnostic of advanced or chronic gout Also called chalkstone
[from Latin, variant of tōfus tufa, tuff]
tophaceous  [təʊˈfeɪʃəs] adj
ThesaurusLegend:  Synonyms Related Words Antonyms
Noun1.tophus - a deposit of urates around a joint or in the external eartophus - a deposit of urates around a joint or in the external ear; diagnostic of advanced or chronic gout
urate - a salt of uric acid
2.tophus - an incrustation that forms on the teeth and gumstophus - an incrustation that forms on the teeth and gums
crust, encrustation, incrustation - a hard outer layer that covers something


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Suspected tophus (deposit or accumulation of uric acid crystals under the skin) Laboratory factors such as ?
The hyperintense signal intensity seen on T2W spin-echo images may reflect the high protein content in the amorphous center of the tophus, while the decreased signal intensity may indicate regions of calcification within the tophus, fibrous tissue and crystals, hemosiderin deposition, or proton immobility.
Although the rapid decline in his ambulatory status may not be explained completely by the chronicity of tophaceous gout, it does perhaps suggest that the tophus was undergoing a phase of acute inflammation, with cellular infiltration and inflammatory exudate formation, producing pain and resulting in a critical size increase, which was sufficient enough to produce clinical evidence of cord compression.
 
 
 
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