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transactivate

   Also found in: Wikipedia 0.01 sec.
trans·ac·ti·vate  (trns-kt-vt, trnz-)
tr.v. trans·ac·ti·vat·ed, trans·ac·ti·vat·ing, trans·ac·ti·vates
To stimulate (a host cell) to replicate the genetic components of a virus. Used of a viral protein.

transac·ti·vation n.
trans·acti·vator n.


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The authors suggest that abnormalities of proliferation regulation in endometrial tumors may be connected with accumulation of mutant p53 protein, its disability to transactivate such target genes as p21, with changes in expression of p16 protein.
ATM targets p53 protein, a transcription factor that can bind to specific DNA sequences and transactivate certain p53-responsive genes while DNA-PK targets mdm2.
A transforming fragment within the direct repeat region of human herpesvirus type 6 that transactivates HIV-1.
 
 
 
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