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transactivate
(redirected from transactivator)

    Also found in: Wikipedia 0.01 sec.
trans·ac·ti·vate  (trns-kt-vt, trnz-)
tr.v. trans·ac·ti·vat·ed, trans·ac·ti·vat·ing, trans·ac·ti·vates
To stimulate (a host cell) to replicate the genetic components of a virus. Used of a viral protein.
transac·ti·vation n.
trans·acti·vator n.
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Proteins called transcription factors, also termed transactivators or trans-acting factors, bind to DNA and regulate RNA polymerase activity, affecting gene expression either by inducing or activating the gene or by inhibiting the gene by reducing transcription levels.
Basic Concepts of Molecular Pathology by Timothy Craig Allen and Philip T Cagle and Helmut H Popper / Archives of Pathology & Laboratory Medicine
Human immunodeficiency virus transactivator protein (Tat) stimulates chemotaxis, calcium mobilization, and activation of human polymorphonuclear leukocytes: implications for Tat-mediated pathogenesis.
Angiogenesis and the tumour microenvironment by Almendro, Vanessa; Gascon, Pere / Advances in Gastrointestinal Cancer
Most remarkable, delNS1 virus was highly attenuated in mice but replicated and caused disease in STAT1 knockout mice, which lack one of the key transactivator molecules needed for the IFN[alpha]/[beta] response (15).
Antiviral response in pandemic influenza viruses by Garcia-Sastre, Adolfo / Emerging Infectious Diseases
 
 
 
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