Entre ellas la hematuria, micro y macroscopica (2%), con necesidad transfusional
inferior a 1%, el hematoma perirrenal y el dolor en la zona de puncion.
Chagas disease: current epidemiological trends after the interruption of vectorial and transfusional
transmission in the Southern Cone countries.
2 trial in pediatric and adult patients with transfusional
It is organized into eight sections: developmental hematology, erythrocyte disorders, platelet disorders, leukocyte disorders, immunologic disorders, hemostatic disorders, transfusional
medicine, and miscellaneous.
In contrast, secondary causes bypass the governing mechanism in the gastrointestinal tract, for example transfusional
Autopsy reports in some patients have shown significant iron deposition in the thyroid gland, suggesting that the etiology of the primary thyroid failure might well be transfusional
hemosiderosis and subsequent cellular damage to the thyroid gland (2).
In the last two decades, transfusional
and iron-chelation therapies have improved the survival of TM patients.
In our study, we observed a low incidence of hepatic fibrosis (30%), which was mostly grade 1 and 2, suggesting that the effect of transfusional
iron overload is not a compelling cause of liver cirrhosis, a process that may take many years to develop.
There remains a significant unmet need for a once-a-day, oral iron chelator in a convenient dosage form for the treatment of transfusional
iron overload with a better safety profile than currently available treatments[sup.
Pathophysiology of transfusional
iron overload: contrasting patterns in thalassemia major and sickle cell disease.
18,19) A recent consensus statement was published regarding the criteria for iron chelation in patients with transfusional
iron overload in MDS (see Table II).
Concepts and goals in the management of transfusional