announces that it has been awarded a $250,000 grant from the Massachusetts Life Sciences Center (MLSC) to fund a collaboration with Transgene
, a French biopharmaceutical company developing innovative immunotherapies for oncology and infectious diseases.
A copy of the management presentation will be accessible by visiting the Transgene
Surveying current research in plant biotechnology, the 16 papers cover transformations mediated by Agrobacterium; other transformation technologies; vectors, promoters, and other tools for plant transformations; transgene
integration, stability, methylation, silencing; and selection systems, marker-free transformation.
, which is unprofitable and hopes to have its first product on the market in 2015, wants to expand in the field to diversify from the development of therapeutic vaccines, its main business, Archinard said.
Along with Alexandre Merieux and the management teams, he outlined the many strengths that Institut Merieux and its companies-bioMerieux, Transgene
, ABL and Silliker- will rely upon to meet these challenges in three strategic areas:
Dow Agrosciences LLC (Indianapolis, IN) has patented a plant cell culture for producing proteinaceous agents comprising a plant cell line stably transformed to express a transgene
encoding a proteinaceous agent and a growth medium which supports the growth of said plant cell culture but which does not support the growth of Mycoplasmataceae and contains no materials of animal origin.
Although pronuclear microinjection has been used for decades to produce transgenic animals, variable transgene
expression patterns and uncertain transmission through the germ line preclude widespread application of this technology.
For the most part, the therapeutic effect of a gene therapy transgene
occurs via three distinct mechanisms, which depend on the type of transgene
To obtain the TH/bZIP-eGFP (enhanced GFP) transgene
, we proceeded in two steps.
Another protective strategy would be to engineer chickens with RNAi transgene
to suppress expression of the Ns1 gene.
If the transgene
is transferred to weeds, then the weeds will be resistant to a very broad spectrum of herbicides," Doty notes.
This is the first example of what might happen if a beneficial transgene
accidentally spread to a wild population and then proliferated in subsequent generations," says Allison Snow, study co-author and professor of evolution, ecology and organismal biology at Ohio State University.