tricyclic antidepressant


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tricyclic antidepressant

n. Abbr. TCA
Any of a group of antidepressant drugs, such as amitryptyline, that contain three fused benzene rings and that block the reuptake of the neurotransmitters norepinephrine and serotonin in the central nervous system.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.tricyclic antidepressant - an antidepressant drug that acts by blocking the reuptake of norepinephrine and serotonin and thus making more of those substances available to act on receptors in the brain
amitriptyline, amitriptyline hydrochloride, Elavil - a tricyclic antidepressant drug (trade name Elavil) with serious side effects; interacts with many other medications
antidepressant, antidepressant drug - any of a class of drugs used to treat depression; often have undesirable side effects
clomipramine - a tricyclic antidepressant drug
desipramine - a tricyclic antidepressant drug that activates the psychomotor system
Adapin, doxepin, doxepin hydrochloride, Sinequan - a tricyclic antidepressant (trade names Adapin and Sinequan) with numerous side effects (dry mouth and sedation and gastrointestinal disturbances)
Imavate, imipramine, impramine hydrochloride, Tofranil - a tricyclic antidepressant (trade names Imavate and Tofranil) used to treat clinical depression
nortriptyline, Pamelor - a tricyclic antidepressant drug (trade name Pamelor) used along with psychotherapy to treat dysthymic depression; may interact dangerously if taken with other drugs
protriptyline - tricyclic antidepressant used to treat clinical depression
Surmontil, trimipramine - tricyclic antidepressant drug (trade name Surmontil) used to treat depression and anxiety and (sometimes) insomnia
References in periodicals archive ?
Most patients who die of an overdose of a tricyclic antidepressant are pronounced dead without reaching a hospital, and those who die after arriving in the emergency room do so within a few hours.
Guidelines in Emergency Medicine Network (GEMNet): guideline for the management of tricyclic antidepressant overdose.
Clinical pharmacokinetics of tricyclic antidepressant overdose.
Compared directly with tricyclic antidepressants, SSRIs were associated with significantly higher rates of all-cause death (adjusted hazard ratio, 1.
Due to a small number of respondents in the caffeine and experimental medication groups, chi-square analysis was performed only with the CNS stimulant and tricyclic antidepressant medication groups.
This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995 concerning CombinatoRx, the scope of its United States patent relating to tricyclic antidepressant and glucocorticosteriod combinations, including CRx-191, the timing of potential future patent issuances, its product candidate CRx-191 and its clinical potential, its plans for clinical, preclinical and formulation development of its product candidates, its business plans and its drug discovery technology.
ETS6103's profile may offer benefit to patients who have not successfully responded to an SSRI and it may have fewer side-effects and superior tolerance when compared to a tricyclic antidepressant.
A Cochrane review of antidepressants for neuropathic pain included 5 RCTs of tricyclic antidepressant use in patients with diabetic neuropathy.
Continuous dysesthesia types of pain are frequently treated initially with tricyclic antidepressant agents.
A large population-based study has shown a link between tricyclic antidepressant medications and an increased risk of cardiovascular disease, adding to a growing body of evidence that the medications carry cardiovascular risks--both for people with and without existing disease.