tricyclic antidepressant


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tricyclic antidepressant

n. Abbr. TCA
Any of a group of antidepressant drugs, such as amitryptyline, that contain three fused benzene rings and that block the reuptake of the neurotransmitters norepinephrine and serotonin in the central nervous system.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.tricyclic antidepressant - an antidepressant drug that acts by blocking the reuptake of norepinephrine and serotonin and thus making more of those substances available to act on receptors in the brain
amitriptyline, amitriptyline hydrochloride, Elavil - a tricyclic antidepressant drug (trade name Elavil) with serious side effects; interacts with many other medications
antidepressant, antidepressant drug - any of a class of drugs used to treat depression; often have undesirable side effects
clomipramine - a tricyclic antidepressant drug
desipramine - a tricyclic antidepressant drug that activates the psychomotor system
Adapin, doxepin, doxepin hydrochloride, Sinequan - a tricyclic antidepressant (trade names Adapin and Sinequan) with numerous side effects (dry mouth and sedation and gastrointestinal disturbances)
Imavate, imipramine, impramine hydrochloride, Tofranil - a tricyclic antidepressant (trade names Imavate and Tofranil) used to treat clinical depression
nortriptyline, Pamelor - a tricyclic antidepressant drug (trade name Pamelor) used along with psychotherapy to treat dysthymic depression; may interact dangerously if taken with other drugs
protriptyline - tricyclic antidepressant used to treat clinical depression
Surmontil, trimipramine - tricyclic antidepressant drug (trade name Surmontil) used to treat depression and anxiety and (sometimes) insomnia
References in periodicals archive ?
Guidelines in Emergency Medicine Network (GEMNet): guideline for the management of tricyclic antidepressant overdose.
Tricyclic antidepressants (TCAs) are widely prescribed for several indications in South Africa.
In a cohort study of 14,784 adults without known CVD in Scotland, the use of tricyclic antidepressants (TCAs) for any amount of time and for any reason was associated with a 35% higher risk of being diagnosed with CVD within 8 years, even after accounting for potential confounders, including symptoms of anxiety and depression, which are also linked to CVD.
Tricyclic antidepressant overdosage: Experimental studies on the management of circulatory complications.
Electrocardiographic criteria for tricyclic antidepressant cardiotoxicity.
Relationship between clinical features of tricyclic antidepressant poisoning and plasma concentrations in children.
Due to a small number of respondents in the caffeine and experimental medication groups, chi-square analysis was performed only with the CNS stimulant and tricyclic antidepressant medication groups.
Compared directly with tricyclic antidepressants, SSRIs were associated with significantly higher rates of all-cause death (adjusted hazard ratio, 1.
Antidepressants fall into a middle ground, with available data revealing a potentially high risk of carcinogenicity in 40% of monoamine oxidase inhibitors (MAOIs), 33% of modern antidepressants (including selective serotonin reuptake inhibitors [SSRIs]), and 22% of tricyclic antidepressants.
We encountered a case of refractory hypotension following epidural administration of local anaesthetic during general anaesthesia in a patient who had been on long-term tricyclic antidepressant therapy continued until the day before surgery.
Clomipramine, known as a tricyclic antidepressant, has been use for more than 30 years.