Table 1 CPIC gene/drug combinations with guidelines for psychiatry (a) Gene Drug(s) CYP2D6 Amitriptyline, fluvoxamine, nortriptyline, paroxetine, clomipramine, desipramine, doxepin, imipramine, trimipramine
CYP2C19 Amitriptyline, citalopram, escitalopram, clomipramine, doxepin, imipramine, trimipramine
, sertraline HLA-B Carbamazepine (a) As of April 2017 CPIC: Clinical Pharmacogenomics Implementation Consortium; CYP: cytochrome P450; HLA-B: human leukocyte antigen complex B Source: Reference 5 Table 2 Ms.
Annual spend - PS4,540,351 | Trimipramine
- a tricyclic antidepressant, which NHS England says costs "significantly more" than others which are available.
Until recently, only a few antidepressants have been demonstrated with no apparent REM sleep inhibition, such as trimipramine
(Riemann et al.
Today, he takes only an antidepressant, trimipramine
, to help him sleep- "all the speed and coke f***ed up my sleep pattern" - and aspirin for the blood.
Today, he takes only one anti-depressant, trimipramine
, to help him sleep - "all the speed and coke I used to take f***ed up my sleep pattern" - and aspirin for his blood.
Today, the only drug he takes is an anti-depressant, trimipramine
, to help him sleep - "all the speed and coke f**f ed up my sleep pattern" - and aspirin for his blood.
Some of the most frequently prescribed tricyclics are amitriptyline (Elavil), desipramine (Norpramin), clomipramine (Anafranil), doxepin (Sinequan), imipramine, (Tofranil), nortriptyline (Pamelor, Aventyl), protriptyline (Vivactil) and trimipramine
Rhotrimine Tablets Rhodiapharm (Canada) (Canada) (discontinued 2006) Typhoid vaccine, Vivotif (Canada) Crucell Switzerland Ltd.
Patient Age [greater than Antidepressant or equal to]65 <65 Sertraline 25 50 Paroxetine 10 20 Citalopram * 20 20 Fluoxetine 10 20 Fluvoxamine * 100 100 Amitriptyline NR 50 Desipramine 25 100 Doxepin 30 75 Imipramine 30 75 Nortriptyline 30 75 Protriptyline 15 15 Trimipramine
50 75 Clomipramine 75 75 Trazodone 25 150 Buproprion 50 200 Phenelzine 45 45 Tranylcypromine 20 20 Maprotiline 25 75 Nefazodone 100 200 Venlafaxine 50 75 Mirtazapine 15 15 Amoxapine 50 100 * These antidepressants were not addressed in 1997 Department of Veterans Affairs depression guidelines; minimum daily dosage for these medications derived from expert consensus.