prevents intestinal inflammation in the trinitrobenzene
sulphonic acid model of rat colitis.
The protective effect of ABA has been demonstrated against trinitrobenzene
sulphonic acid- (TNBS-) induced colitis in Swiss male mice .
METHODS: Experimental colitis was induced with 1 mL trinitrobenzene
sulfonic acid (TNBS) in 40% ethanol by intracolonic administration with 8-cm-long cannula under ether anesthesia to rats in colitis group and colitis + black cumin oil group.
In this study a fraction containing the lactone sesquiterpene onopordopicrin (ONP) from Arctium lappa was administered orally as either 25mg/kg daily or 50mg/kg daily 48, 24 and 1 hour before the induction of colitis in rats by the administration of 2,4,6 trinitrobenzene
sulfonic acid (TNBS).
73) IL-13 has also been shown to be important in a surprising variety of extrapulmonary fibrosis models, including non-immune-based systems such as steatohepatitis and trinitrobenzene
sulfonic acid-induced colitis.
The aims of this study were to investigate, if the inflammation markers formed in trinitrobenzene
sulphonic acid (TNBS)-induced colitis affect the gastric tissue and to determine the possible protective effects of orally administered NS seed oil on the gastric tissue.
Zona-free blastocysts were placed at 4[degrees]C for 30 min in 15 mM trinitrobenzene
sulfonic acid (TNBS, Sigma) and then exposed to goat anti-dinitrophenol-BSA (ICN Biomedicals Inc.