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troglitazone

   Also found in: Medical, Wikipedia 0.01 sec.
tro·gli·ta·zone  (trgl-t-zn)
n.
An oral antidiabetic agent that lowers blood glucose by improving the response of target cells to insulin without increasing insulin secretion.

[tro-, of unknown meaning + gli- (ultimately shortening and alteration of hypoglycemia) + t(hi)az(olidinedi)one, one of its constituents.]


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46) In studies in PCOS women, troglitazone reduced PAI-1 levels (47) and improved endothelium-dependent vasodilation.
Pharmacologic therapy--including metformin, acarbose, troglitazone, and orlistat--also has been shown to reduce the risk of progression to diabetes.
A fourth group was treated with the drug troglitazone (Rezulin), but this part of the study was discontinued after researchers discovered that troglitazone can cause serious liver damage.
 
 
 
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