In vitro trypanocidal
activity of triterpenes from Miconia species.
drugs can be useful, parasite resistance to these drugs increases yearly.
In-vivo assessment of effects of trypanocidal
drugs against the Trypanosoma evansi isolates from Philippine water buffaloe (Bubalus bubalis), Veter: arhiv, 83(4), 381-392 (2013)
The National Chagas Program (NCP) in Argentina (7) seeks to optimize early diagnosis and timely treatment of acute and chronic Chagas infection, through design and distribution of patient care guidelines (8) and the purchase and free distribution of trypanocidal
medication by the Argentine Ministry of Health to provincial Chagas disease programs.
Ferrocenyl diamine hydrochlorides showed trypanocidal
activity and the expression of 25.
In the treated group, the lack of reduction in parasite load is most likely attributable to the reported inability of Cur to act directly as a trypanocidal
agent in the rodent model of infection, as achievable serum and tissue levels are much lower than drug concentrations required for in vitro T.
, leishmanicidal and antifungal potential from marine red alga Bostrychia tenella J.
drug benznidazole impairs lipopolysaccharide induction of macrophage nitric oxide synthase gene transcription through inhibition of NF-[kappa]B activation.
The antitumoral, trypanocidal
and antileishmanial activities of extract and alkaloids isolated from Duguetia furfuracea" Phytomedicine, vol.
Gonzalez-Rosende, Nuclease activity and ultrastructural effects of new sulfonamides with anti-leishmanial and trypanocidal
drugs for chronic asymptomatic Trypanosoma cruzi infection.
Furthermore, the trypanocidal
potential increased with the increase in the number of carbons found on the side chain until reaching the maximum activity, in this case at n-undecyl gallate (12), and longer carbon chains showed lower trypanocidal
activity, reaching a cutoff at n-tetradecyl gallate (14).